50-167-9323

PGR Monoclonal Antibody (OTI2E2), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-9323-Each-of-1 In Stock ₹ 43,217.21

50-167-9323 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PGR

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P06401

Gene Symbols

PGR

Immunogen

Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2E2

Conjugate

Unconjugated

Gene

PGR

Gene Alias

NR3C3, PR

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5241

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The progesterone receptor (PR) is a member of the steroid family of nuclear receptors
  • The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintece of pregcy
  • PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites
  • PR-B is the transcriptionally active form and is responsible for activating genes for the maintece of the endometrium, maintece of pregcy, and inhibition of ovulation
  • PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus
  • This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity
  • In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins
  • Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription
  • A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

Compare Similar Items

Show Difference

Img

OriGene

50-167-9323

--


Antigen:
PGR

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2E2

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
NR3C3, PR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-9325

--


Antigen:
BRCA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1151-1473 of human BRCA1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI5D10

Conjugate:
Unconjugated

Gene:
BRCA1

Gene Alias:
BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-9326

--


Antigen:
BRCA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1151-1473 of human BRCA1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2A5

Conjugate:
Unconjugated

Gene:
BRCA1

Gene Alias:
BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-167-9328

--


Antigen:
PARN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O95453

Gene Symbols:
PARN

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-266 of human PARN produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI4E12

Conjugate:
Unconjugated

Gene:
PARN

Gene Alias:
DAN, DKCB6, PFBMFT4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5073

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid