50-168-0552
PGR Monoclonal Antibody (OTI4C12), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-0552-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-0552 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
PGR
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P06401
Gene Symbols
PGR
Immunogen
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI4C12
Conjugate
Unconjugated
Gene
PGR
Gene Alias
NR3C3, PR
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5241
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- The progesterone receptor (PR) is a member of the steroid family of nuclear receptors
- The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintece of pregcy
- PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites
- PR-B is the transcriptionally active form and is responsible for activating genes for the maintece of the endometrium, maintece of pregcy, and inhibition of ovulation
- PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus
- This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity
- In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins
- Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription
- A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.
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Antigen: PGR
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P06401
Gene Symbols: PGR
Immunogen: Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4C12
Conjugate: Unconjugated
Gene: PGR
Gene Alias: NR3C3, PR
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5241
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PGR
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P06401
Gene Symbols:
PGR
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI4C12
Conjugate:
Unconjugated
Gene:
PGR
Gene Alias:
NR3C3, PR
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5241
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PGR
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P06401
Gene Symbols: PGR
Immunogen: Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI16H2
Conjugate: Unconjugated
Gene: PGR
Gene Alias: NR3C3, PR
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5241
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PGR
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P06401
Gene Symbols:
PGR
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-298 of human PGR produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI16H2
Conjugate:
Unconjugated
Gene:
PGR
Gene Alias:
NR3C3, PR
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5241
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NKX3.1
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q99801
Gene Symbols: NKX3-1
Immunogen: Full length human recombit protein of human NKX3-1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1B9
Conjugate: Unconjugated
Gene: NKX3-1
Gene Alias: BAPX2, NKX3, NKX3.1, NKX3A
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4824
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NKX3.1
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q99801
Gene Symbols:
NKX3-1
Immunogen:
Full length human recombit protein of human NKX3-1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1B9
Conjugate:
Unconjugated
Gene:
NKX3-1
Gene Alias:
BAPX2, NKX3, NKX3.1, NKX3A
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4824
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NCOA2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q15596
Gene Symbols: NCOA2
Immunogen: Human recombit protein fragment corresponding to amino acids 1-280 of human NCOA2 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI3C7
Conjugate: Unconjugated
Gene: NCOA2
Gene Alias: GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10499
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NCOA2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q15596
Gene Symbols:
NCOA2
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-280 of human NCOA2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI3C7
Conjugate:
Unconjugated
Gene:
NCOA2
Gene Alias:
GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10499
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid