50-168-0820

IGF1 Monoclonal Antibody (OTI3A5), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-0820-Each-of-1 In Stock ₹ 43,217.21

50-168-0820 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

IGF1

Classification

Monoclonal

Conjugate

Unconjugated

Gene

IGF1

Gene Alias

IGF-I, IGFI, MGF

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3479

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

OTI3A5

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P05019

Gene Symbols

IGF1

Immunogen

Human recombit protein fragment corresponding to amino acids 1-151 of human IGF1 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
  • A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
  • Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
  • IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
  • In circulation, IGFs are predomitly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
  • IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
  • Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
  • Low levels of IGF1 have been linked to Alzheimer′s disease
  • IGF1 is processed from a precursor, bound by a specific receptor, and secreted
  • Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.

Compare Similar Items

Show Difference

Img

OriGene

50-168-0820

--


Antigen:
IGF1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IGF1

Gene Alias:
IGF-I, IGFI, MGF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3479

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI3A5

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P05019

Gene Symbols:
IGF1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-151 of human IGF1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-0821

--


Antigen:
ROS1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ROS1

Gene Alias:
MCF3, ROS, c-ros-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6098

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI5D2

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08922

Gene Symbols:
ROS1

Immunogen:
Human recombit protein fragment corresponding to amino acids 2126-2347 of human ROS1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-0822

--


Antigen:
RET

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RET

Gene Alias:
CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5979

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4H3

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P07949

Gene Symbols:
RET

Immunogen:
Human recombit protein fragment corresponding to amino acids 713-1017 of human RET produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-0824

--


Antigen:
IGF1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IGF1

Gene Alias:
IGF-I, IGFI, MGF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3479

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4B12

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P05019

Gene Symbols:
IGF1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-151 of human IGF1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a