50-168-0843

IGF1 Monoclonal Antibody (OTI3A6), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-0843-Each-of-1 In Stock ₹ 43,217.21

50-168-0843 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

IGF1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P05019

Gene Symbols

IGF1

Immunogen

Human recombit protein fragment corresponding to amino acids 1-151 of human IGF1 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI3A6

Conjugate

Unconjugated

Gene

IGF1

Gene Alias

IGF-I, IGFI, MGF

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3479

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
  • A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
  • Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
  • IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
  • In circulation, IGFs are predomitly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
  • IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
  • Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
  • Low levels of IGF1 have been linked to Alzheimer′s disease
  • IGF1 is processed from a precursor, bound by a specific receptor, and secreted
  • Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.

Compare Similar Items

Show Difference

Img

OriGene

50-168-0843

--


Antigen:
IGF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P05019

Gene Symbols:
IGF1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-151 of human IGF1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3A6

Conjugate:
Unconjugated

Gene:
IGF1

Gene Alias:
IGF-I, IGFI, MGF

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3479

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-0844

--


Antigen:
MET

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08581

Gene Symbols:
MET

Immunogen:
Human recombit protein fragment corresponding to amino acids 570-885 of human MET produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E6

Conjugate:
Unconjugated

Gene:
MET

Gene Alias:
AUTS9, DFNB97, HGFR, RCCP2, c-Met

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4233

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-0845

--


Antigen:
MET

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08581

Gene Symbols:
MET

Immunogen:
Human recombit protein fragment corresponding to amino acids 570-885 of human MET produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3G5

Conjugate:
Unconjugated

Gene:
MET

Gene Alias:
AUTS9, DFNB97, HGFR, RCCP2, c-Met

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4233

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-0846

--


Antigen:
IFNG

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P01579

Gene Symbols:
IFNG

Immunogen:
Human recombit protein fragment corresponding to amino acids 24-166 of human IFNG produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1G7

Conjugate:
Unconjugated

Gene:
IFNG

Gene Alias:
IFG, IFI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3458

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid