50-168-1032

RARA Monoclonal Antibody (OTI2D2), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1032-Each-of-1 In Stock ₹ 43,217.21

50-168-1032 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

RARA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P10276

Gene Symbols

RARA

Immunogen

Human recombit protein fragment corresponding to amino acids 52-299 of human RARA produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI2D2

Conjugate

Unconjugated

Gene

RARA

Gene Alias

NR1B1, RAR

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5914

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • RARA is a receptor for retinoic acid
  • Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes
  • The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5′-AGGTCA-3′ sites known as DR1-DR5
  • In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression
  • On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation
  • RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis
  • Has a role in the survival of early spermatocytes at the beginning prophase of meiosis
  • In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes
  • In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function
  • Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5
  • Mediates retinoic acid-induced granulopoiesis.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1032

--


Antigen:
RARA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P10276

Gene Symbols:
RARA

Immunogen:
Human recombit protein fragment corresponding to amino acids 52-299 of human RARA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2D2

Conjugate:
Unconjugated

Gene:
RARA

Gene Alias:
NR1B1, RAR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5914

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1035

--


Antigen:
PCBP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q15365

Gene Symbols:
PCBP1

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-225 of human PCBP1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3B9

Conjugate:
Unconjugated

Gene:
PCBP1

Gene Alias:
HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5093

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1036

--


Antigen:
CCND2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P30279

Gene Symbols:
CCND2

Immunogen:
Full length human recombit protein of human CCND2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI1E4

Conjugate:
Unconjugated

Gene:
CCND2

Gene Alias:
KIAK0002, MPPH3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
894

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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OriGene

50-168-1038

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Antigen:
GLI4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P10075

Gene Symbols:
GLI4

Immunogen:
Full length human recombit protein of human GLI4 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI3A9

Conjugate:
Unconjugated

Gene:
GLI4

Gene Alias:
HKR4, ZNF928

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2738

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid