50-168-1130

RARA Monoclonal Antibody (OTI2C3), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1130-Each-of-1 In Stock ₹ 43,217.21

50-168-1130 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

RARA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P10276

Gene Symbols

RARA

Immunogen

Human recombit protein fragment corresponding to amino acids 52-299 of human RARA produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2C3

Conjugate

Unconjugated

Gene

RARA

Gene Alias

NR1B1, RAR

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5914

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • RARA is a receptor for retinoic acid
  • Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes
  • The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5′-AGGTCA-3′ sites known as DR1-DR5
  • In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression
  • On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation
  • RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis
  • Has a role in the survival of early spermatocytes at the beginning prophase of meiosis
  • In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes
  • In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function
  • Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5
  • Mediates retinoic acid-induced granulopoiesis.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1130

--


Antigen:
RARA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P10276

Gene Symbols:
RARA

Immunogen:
Human recombit protein fragment corresponding to amino acids 52-299 of human RARA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2C3

Conjugate:
Unconjugated

Gene:
RARA

Gene Alias:
NR1B1, RAR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5914

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1132

--


Antigen:
NARS2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q96I59

Gene Symbols:
NARS2

Immunogen:
Full length human recombit protein of human NARS2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI10C10

Conjugate:
Unconjugated

Gene:
NARS2

Gene Alias:
DFNB94, SLM5, asnRS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79731

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1133

--


Antigen:
NARS2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q96I59

Gene Symbols:
NARS2

Immunogen:
Full length human recombit protein of human NARS2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI10G5

Conjugate:
Unconjugated

Gene:
NARS2

Gene Alias:
DFNB94, SLM5, asnRS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79731

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1136

--


Antigen:
NARS2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q96I59

Gene Symbols:
NARS2

Immunogen:
Full length human recombit protein of human NARS2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8D10

Conjugate:
Unconjugated

Gene:
NARS2

Gene Alias:
DFNB94, SLM5, asnRS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79731

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid