50-168-1180
BCL2 Monoclonal Antibody (OTI5H8), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-1180-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-1180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
BCL2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P10415
Gene Symbols
BCL2
Immunogen
Full length human recombit protein of human BCL2 produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Western Blot
Clone
OTI5H8
Conjugate
Unconjugated
Gene
BCL2
Gene Alias
Bcl-2, PPP1R50
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
596
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
Compare Similar Items
Show Difference
Antigen: BCL2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P10415
Gene Symbols: BCL2
Immunogen: Full length human recombit protein of human BCL2 produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Western Blot
Clone: OTI5H8
Conjugate: Unconjugated
Gene: BCL2
Gene Alias: Bcl-2, PPP1R50
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 596
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BCL2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P10415
Gene Symbols:
BCL2
Immunogen:
Full length human recombit protein of human BCL2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
OTI5H8
Conjugate:
Unconjugated
Gene:
BCL2
Gene Alias:
Bcl-2, PPP1R50
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
596
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: GABRA5
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P31644
Gene Symbols: GABRA5
Immunogen: Human recombit protein fragment corresponding to amino acids 32-259 of human GABRA5 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI1G5
Conjugate: Unconjugated
Gene: GABRA5
Gene Alias: gamma-aminobutyric acid type A receptor alpha5 subunit
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2558
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
GABRA5
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P31644
Gene Symbols:
GABRA5
Immunogen:
Human recombit protein fragment corresponding to amino acids 32-259 of human GABRA5 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI1G5
Conjugate:
Unconjugated
Gene:
GABRA5
Gene Alias:
gamma-aminobutyric acid type A receptor alpha5 subunit
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2558
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: UBE2D2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P62837
Gene Symbols: UBE2D2
Immunogen: Full length human recombit protein of human UBE2D2 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Western Blot
Clone: OTI3H1
Conjugate: Unconjugated
Gene: UBE2D2
Gene Alias: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7322
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
UBE2D2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P62837
Gene Symbols:
UBE2D2
Immunogen:
Full length human recombit protein of human UBE2D2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Western Blot
Clone:
OTI3H1
Conjugate:
Unconjugated
Gene:
UBE2D2
Gene Alias:
E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7322
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: WIBG
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q9BRP8
Gene Symbols: PYM1
Immunogen: Full length human recombit protein of human WIBG produced in HEK293T cell.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2C1
Conjugate: Unconjugated
Gene: PYM1
Gene Alias: PYM, WIBG
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84305
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
WIBG
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q9BRP8
Gene Symbols:
PYM1
Immunogen:
Full length human recombit protein of human WIBG produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2C1
Conjugate:
Unconjugated
Gene:
PYM1
Gene Alias:
PYM, WIBG
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84305
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid