50-168-1434
CD3 Monoclonal Antibody (UCHT1), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-1434-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-1434 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
CD3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P07766
Gene Symbols
CD3E
Immunogen
Human infant thymocytes and lymphocytes from a patient with Sezary disease
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Western Blot
Clone
UCHT1
Conjugate
Unconjugated
Gene
CD3E
Gene Alias
IMD18; T3E; TCRE; HCD3
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
916
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- CD3 epsilon is part of the CD3 subunit complex which is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex
- T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta
- These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11
- The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits
- CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation
- The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum
- It is never expressed on B or NK cells
- Decreased percentages of T lymphocytes may be observed in some autoimmune diseases
- The genes encoding the CD3 epsilon, gamma and delta polypeptides are located on chromosome 11
- Defects in this gene are associated with T cell immunodeficiency and has been linked to Type 1 Diabetes deficiency in women.
Compare Similar Items
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Antigen: CD3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P07766
Gene Symbols: CD3E
Immunogen: Human infant thymocytes and lymphocytes from a patient with Sezary disease
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Western Blot
Clone: UCHT1
Conjugate: Unconjugated
Gene: CD3E
Gene Alias: IMD18; T3E; TCRE; HCD3
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 916
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CD3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P07766
Gene Symbols:
CD3E
Immunogen:
Human infant thymocytes and lymphocytes from a patient with Sezary disease
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Western Blot
Clone:
UCHT1
Conjugate:
Unconjugated
Gene:
CD3E
Gene Alias:
IMD18; T3E; TCRE; HCD3
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
916
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CD68
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P34810
Gene Symbols: CD68
Immunogen: Lysosomal fraction of human lung macrophages CD68(KP1)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: KP1
Conjugate: Unconjugated
Gene: CD68
Gene Alias: GP110, LAMP4, SCARD1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 968
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CD68
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P34810
Gene Symbols:
CD68
Immunogen:
Lysosomal fraction of human lung macrophages CD68(KP1)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
KP1
Conjugate:
Unconjugated
Gene:
CD68
Gene Alias:
GP110, LAMP4, SCARD1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
968
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: TP53BP1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q12888
Gene Symbols: TP53BP1
Immunogen: Human recombit protein fragment corresponding to amino acids 1-300 of human TP53BP1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI9C8
Conjugate: Unconjugated
Gene: TP53BP1
Gene Alias: 53BP1, TDRD30, TP53, p202, p53BP1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7158
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TP53BP1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q12888
Gene Symbols:
TP53BP1
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-300 of human TP53BP1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI9C8
Conjugate:
Unconjugated
Gene:
TP53BP1
Gene Alias:
53BP1, TDRD30, TP53, p202, p53BP1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7158
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: F12
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P00748
Gene Symbols: F12
Immunogen: Human recombit protein fragment corresponding to amino acids 73-372 of human F12 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin)
Clone: OTI1H5
Conjugate: Unconjugated
Gene: F12
Gene Alias: HAE3, HAEX, HAF
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2161
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
F12
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P00748
Gene Symbols:
F12
Immunogen:
Human recombit protein fragment corresponding to amino acids 73-372 of human F12 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin)
Clone:
OTI1H5
Conjugate:
Unconjugated
Gene:
F12
Gene Alias:
HAE3, HAEX, HAF
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2161
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid