50-168-1652

CDCA8 Monoclonal Antibody (OTI6A8), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1652-Each-of-1 In Stock ₹ 43,217.21

50-168-1652 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

CDCA8

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q53HL2

Gene Symbols

CDCA8

Immunogen

Full length human recombit protein of human CDCA8 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI6A8

Conjugate

Unconjugated

Gene

CDCA8

Gene Alias

BOR, BOREALIN, DasraB, MESRGP

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55143

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle
  • The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division
  • It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase
  • CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues
  • In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation
  • Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53
  • Its aberrant expression is linked to a poor prognosis for gastric cancer.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1652

--


Antigen:
CDCA8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q53HL2

Gene Symbols:
CDCA8

Immunogen:
Full length human recombit protein of human CDCA8 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI6A8

Conjugate:
Unconjugated

Gene:
CDCA8

Gene Alias:
BOR, BOREALIN, DasraB, MESRGP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55143

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1656

--


Antigen:
ATF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P18846

Gene Symbols:
ATF1

Immunogen:
Full length human recombit protein of human ATF1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2C2

Conjugate:
Unconjugated

Gene:
ATF1

Gene Alias:
EWS-ATF1, FUS/ATF-1, TREB36

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
466

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1659

--


Antigen:
IKBKE

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q14164

Gene Symbols:
IKBKE

Immunogen:
Human recombit protein fragment corresponding to amino acids 474-716 of human IKBKE produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1E4

Conjugate:
Unconjugated

Gene:
IKBKE

Gene Alias:
IKK-E, IKK-i, IKKE, IKKI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9641

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1660

--


Antigen:
IKBKE

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q14164

Gene Symbols:
IKBKE

Immunogen:
Human recombit protein fragment corresponding to amino acids 474-716 of human IKBKE produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3C5

Conjugate:
Unconjugated

Gene:
IKBKE

Gene Alias:
IKK-E, IKK-i, IKKE, IKKI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9641

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid