50-168-1662

CDCA8 Monoclonal Antibody (OTI9D1), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-1662-Each-of-1 In Stock ₹ 43,217.21

50-168-1662 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

CDCA8

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q53HL2

Gene Symbols

CDCA8

Immunogen

Full length human recombit protein of human CDCA8 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Western Blot

Clone

OTI9D1

Conjugate

Unconjugated

Gene

CDCA8

Gene Alias

BOR, BOREALIN, DasraB, MESRGP

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55143

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle
  • The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division
  • It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase
  • CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues
  • In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation
  • Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53
  • Its aberrant expression is linked to a poor prognosis for gastric cancer.

Compare Similar Items

Show Difference

Img

OriGene

50-168-1662

--


Antigen:
CDCA8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q53HL2

Gene Symbols:
CDCA8

Immunogen:
Full length human recombit protein of human CDCA8 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI9D1

Conjugate:
Unconjugated

Gene:
CDCA8

Gene Alias:
BOR, BOREALIN, DasraB, MESRGP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55143

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1663

--


Antigen:
POLA2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q14181

Gene Symbols:
POLA2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-284 of human POLA2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3G7

Conjugate:
Unconjugated

Gene:
POLA2

Gene Alias:
DNA polymerase alpha 2, accessory subunit

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23649

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1664

--


Antigen:
POLA2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q14181

Gene Symbols:
POLA2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-284 of human POLA2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2B4

Conjugate:
Unconjugated

Gene:
POLA2

Gene Alias:
DNA polymerase alpha 2, accessory subunit

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23649

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-1665

--


Antigen:
PDGFRA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P16234

Gene Symbols:
PDGFRA

Immunogen:
Human recombit protein fragment corresponding to amino acids 789-1089 of human PDGFRA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI1H10

Conjugate:
Unconjugated

Gene:
PDGFRA

Gene Alias:
CD140A, PDGFR-2, PDGFR2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5156

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid