50-168-2233
CLU Monoclonal Antibody (OTI2A7), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-2233-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-2233 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
CLU
Classification
Monoclonal
Conjugate
Unconjugated
Gene
CLU
Gene Alias
AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1191
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Clone
OTI2A7
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P10909
Gene Symbols
CLU
Immunogen
Human recombit protein fragment corresponding to amino acids 23-227 of human CLU produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
- Prevents stress-induced aggregation of blood plasma proteins
- Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro)
- Does not require ATP
- Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70
- Does not refold proteins by itself
- Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation
- Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement
- Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins
- Promotes proteasomal degradation of COMMD1 and IKBKB
- Modulates NF-kappa-B transcriptional activity
- Nuclear isoforms promote apoptosis
- Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis
- Plays a role in the regulation of cell proliferation.
Compare Similar Items
Show Difference
Antigen: CLU
Classification: Monoclonal
Conjugate: Unconjugated
Gene: CLU
Gene Alias: AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1191
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Clone: OTI2A7
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P10909
Gene Symbols: CLU
Immunogen: Human recombit protein fragment corresponding to amino acids 23-227 of human CLU produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
CLU
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
CLU
Gene Alias:
AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1191
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Clone:
OTI2A7
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P10909
Gene Symbols:
CLU
Immunogen:
Human recombit protein fragment corresponding to amino acids 23-227 of human CLU produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: FOXO4
Classification: Monoclonal
Conjugate: Unconjugated
Gene: FOXO4
Gene Alias: AFX, AFX1, MLLT7
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4303
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI1A4
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P98177
Gene Symbols: FOXO4
Immunogen: Human recombit protein fragment corresponding to amino acids 206-505 of human FOXO4 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
FOXO4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
FOXO4
Gene Alias:
AFX, AFX1, MLLT7
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4303
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI1A4
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P98177
Gene Symbols:
FOXO4
Immunogen:
Human recombit protein fragment corresponding to amino acids 206-505 of human FOXO4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: RBMS1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: RBMS1
Gene Alias: C2orf12, HCC-4, MSSP, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5937
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI2H1
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P29558
Gene Symbols: RBMS1
Immunogen: Full length human recombit protein of human RBMS1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
RBMS1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
RBMS1
Gene Alias:
C2orf12, HCC-4, MSSP, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5937
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI2H1
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P29558
Gene Symbols:
RBMS1
Immunogen:
Full length human recombit protein of human RBMS1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: EGLN2
Classification: Monoclonal
Conjugate: Unconjugated
Gene: EGLN2
Gene Alias: EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 112398
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI7H3
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q96KS0
Gene Symbols: EGLN2
Immunogen: Full length human recombit protein of human EGLN2 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
EGLN2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
EGLN2
Gene Alias:
EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
112398
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI7H3
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q96KS0
Gene Symbols:
EGLN2
Immunogen:
Full length human recombit protein of human EGLN2 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1