50-168-2284
CLU Mouse anti-Human, Clone: OTI5D3, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-2284-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-2284 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
CLU
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P10909
Gene Symbols
CLU
Immunogen
Human recombit protein fragment corresponding to amino acids 23-227 of human CLU produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI5D3
Conjugate
Unconjugated
Gene
CLU
Gene Alias
AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1191
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
- Prevents stress-induced aggregation of blood plasma proteins
- Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro)
- Does not require ATP
- Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70
- Does not refold proteins by itself
- Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation
- Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement
- Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins
- Promotes proteasomal degradation of COMMD1 and IKBKB
- Modulates NF-kappa-B transcriptional activity
- Nuclear isoforms promote apoptosis
- Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis
- Plays a role in the regulation of cell proliferation.
Compare Similar Items
Show Difference
Antigen: CLU
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P10909
Gene Symbols: CLU
Immunogen: Human recombit protein fragment corresponding to amino acids 23-227 of human CLU produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI5D3
Conjugate: Unconjugated
Gene: CLU
Gene Alias: AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1191
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CLU
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P10909
Gene Symbols:
CLU
Immunogen:
Human recombit protein fragment corresponding to amino acids 23-227 of human CLU produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
OTI5D3
Conjugate:
Unconjugated
Gene:
CLU
Gene Alias:
AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1191
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NAPSA
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O96009
Gene Symbols: NAPSA
Immunogen: Human recombit protein fragment corresponding to amino acids 64-244 of human NAPSA produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin)
Clone: OTI3E5
Conjugate: Unconjugated
Gene: NAPSA
Gene Alias: KAP, Kdap, NAP1, NAPA, SNAPA
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9476
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NAPSA
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O96009
Gene Symbols:
NAPSA
Immunogen:
Human recombit protein fragment corresponding to amino acids 64-244 of human NAPSA produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin)
Clone:
OTI3E5
Conjugate:
Unconjugated
Gene:
NAPSA
Gene Alias:
KAP, Kdap, NAP1, NAPA, SNAPA
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9476
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ASPDH
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: A6ND91
Gene Symbols: ASPDH
Immunogen: Full length human recombit protein of human ASPDH produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin)
Clone: OTI4G8
Conjugate: Unconjugated
Gene: ASPDH
Gene Alias: aspartate dehydrogenase domain containing
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 554235
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ASPDH
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
A6ND91
Gene Symbols:
ASPDH
Immunogen:
Full length human recombit protein of human ASPDH produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin)
Clone:
OTI4G8
Conjugate:
Unconjugated
Gene:
ASPDH
Gene Alias:
aspartate dehydrogenase domain containing
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
554235
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: IGFBP1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P08833
Gene Symbols: IGFBP1
Immunogen: Human recombit protein fragment corresponding to amino acids 26-259 of human IGFBP1 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI4E12
Conjugate: Unconjugated
Gene: IGFBP1
Gene Alias: AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3484
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
IGFBP1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P08833
Gene Symbols:
IGFBP1
Immunogen:
Human recombit protein fragment corresponding to amino acids 26-259 of human IGFBP1 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI4E12
Conjugate:
Unconjugated
Gene:
IGFBP1
Gene Alias:
AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3484
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid