50-168-2702

GNAS Monoclonal Antibody (OTI12D9), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-2702-Each-of-1 In Stock ₹ 43,217.21

50-168-2702 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

GNAS

Classification

Monoclonal

Conjugate

Unconjugated

Gene

GNAS

Gene Alias

AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2778

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

OTI12D9

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P84996

Gene Symbols

GNAS

Immunogen

Full length human recombit protein of human GNAS produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Mutations in GNAS gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors
  • This gene has a highly complex imprinted expression pattern
  • It encodes maternally, paternally, and biallelically expressed proteins which are derived from alternatively spliced transcripts with alternate 5′ exons
  • Each of the upstream exons is within a differentially methylated region, commonly found in imprinted genes
  • However, the close proximity (14 kb) of two oppositely expressed promoter regions is unusual
  • In addition, one of the alternate 5′ exons introduces a frameshift relative to the other transcripts, resulting in one isoform which is structurally unrelated to the others
  • An antisense transcript exists, and may regulate imprinting in this region
  • Mutations in this gene result in pseudohypoparathyroidism type 1a (PHP1a), which has an atypical autosomal domit inheritance pattern requiring maternal transmission for full penetrance
  • Other transcript variants including four additional exons have been described; however, their full length sequences have not been determined.

Compare Similar Items

Show Difference

Img

OriGene

50-168-2702

--


Antigen:
GNAS

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GNAS

Gene Alias:
AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2778

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI12D9

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P84996

Gene Symbols:
GNAS

Immunogen:
Full length human recombit protein of human GNAS produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-2703

--


Antigen:
GNAS

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
GNAS

Gene Alias:
AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2778

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI7A4

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P84996

Gene Symbols:
GNAS

Immunogen:
Full length human recombit protein of human GNAS produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-2704

--


Antigen:
CTSL1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CTSL

Gene Alias:
CATL, CTSL1, MEP

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1514

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2F1

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P07711

Gene Symbols:
CTSL

Immunogen:
Full length human recombit protein of human CTSL produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-2706

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Antigen:
RING1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RING1

Gene Alias:
RING1A, RNF1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6015

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3G7

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q06587

Gene Symbols:
RING1

Immunogen:
Human recombit protein fragment corresponding to amino acids 88-362 of human RING1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1