50-168-2711

GNAS Monoclonal Antibody (OTI13G5), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-2711-Each-of-1 In Stock ₹ 43,217.21

50-168-2711 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

GNAS

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P84996

Gene Symbols

GNAS

Immunogen

Full length human recombit protein of human GNAS produced in HEK293T Cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI13G5

Conjugate

Unconjugated

Gene

GNAS

Gene Alias

AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2778

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Mutations in GNAS gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors
  • This gene has a highly complex imprinted expression pattern
  • It encodes maternally, paternally, and biallelically expressed proteins which are derived from alternatively spliced transcripts with alternate 5′ exons
  • Each of the upstream exons is within a differentially methylated region, commonly found in imprinted genes
  • However, the close proximity (14 kb) of two oppositely expressed promoter regions is unusual
  • In addition, one of the alternate 5′ exons introduces a frameshift relative to the other transcripts, resulting in one isoform which is structurally unrelated to the others
  • An antisense transcript exists, and may regulate imprinting in this region
  • Mutations in this gene result in pseudohypoparathyroidism type 1a (PHP1a), which has an atypical autosomal domit inheritance pattern requiring maternal transmission for full penetrance
  • Other transcript variants including four additional exons have been described; however, their full length sequences have not been determined.

Compare Similar Items

Show Difference

Img

OriGene

50-168-2711

--


Antigen:
GNAS

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P84996

Gene Symbols:
GNAS

Immunogen:
Full length human recombit protein of human GNAS produced in HEK293T Cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI13G5

Conjugate:
Unconjugated

Gene:
GNAS

Gene Alias:
AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2778

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2714

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Antigen:
HFE2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q6ZVN8

Gene Symbols:
HFE2

Immunogen:
Human recombit protein fragment corresponding to amino acids 36-263 of human HFE2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI4E2

Conjugate:
Unconjugated

Gene:
HFE2

Gene Alias:
HFE2A, HJV, JH, RGMC

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
148738

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2718

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Antigen:
TCEANC2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q96MN5

Gene Symbols:
TCEANC2

Immunogen:
Full length human recombit protein of human TCEANC2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2D2

Conjugate:
Unconjugated

Gene:
TCEANC2

Gene Alias:
C1orf83

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
127428

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-2719

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Antigen:
TCEANC2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q96MN5

Gene Symbols:
TCEANC2

Immunogen:
Full length human recombit protein of human C1orf83 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI8E11

Conjugate:
Unconjugated

Gene:
TCEANC2

Gene Alias:
C1orf83

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
127428

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid