50-168-3862

PPM1D Mouse anti-Human, Clone: OTI3A7, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-3862-Each-of-1 In Stock ₹ 43,217.21

50-168-3862 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PPM1D

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O15297

Gene Symbols

PPM1D

Immunogen

Human recombit protein fragment corresponding to amino acids 1-375 of human PPM1D produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI3A7

Conjugate

Unconjugated

Gene

PPM1D

Gene Alias

IDDGIP, PP2C-DELTA, WIP1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8493

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases
  • PP2C family members are known to be negative regulators of cell stress response pathways
  • The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses
  • While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis
  • This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis
  • This gene is located in a chromosomal region known to be amplified in breast cancer
  • The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development.

Compare Similar Items

Show Difference

Img

OriGene

50-168-3862

--


Antigen:
PPM1D

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O15297

Gene Symbols:
PPM1D

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-375 of human PPM1D produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3A7

Conjugate:
Unconjugated

Gene:
PPM1D

Gene Alias:
IDDGIP, PP2C-DELTA, WIP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8493

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3863

--


Antigen:
RNF41

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9H4P4

Gene Symbols:
RNF41

Immunogen:
Full length human recombit protein of human RNF41 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2C1

Conjugate:
Unconjugated

Gene:
RNF41

Gene Alias:
FLRF, NRDP1, SBBI03

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10193

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3864

--


Antigen:
APBB1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O00213

Gene Symbols:
APBB1

Immunogen:
Full length human recombit protein of human APBB1 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3H9

Conjugate:
Unconjugated

Gene:
APBB1

Gene Alias:
FE65, MGC:9072, RIR

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
322

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3870

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Antigen:
SOCS4

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8WXH5

Gene Symbols:
SOCS4

Immunogen:
Full length human recombit protein of human SOCS4 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI5H9

Conjugate:
Unconjugated

Gene:
SOCS4

Gene Alias:
SOCS7

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
122809

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid