50-168-3886

PPM1D Monoclonal Antibody (OTI3E1), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-3886-Each-of-1 In Stock ₹ 43,217.21

50-168-3886 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PPM1D

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O15297

Gene Symbols

PPM1D

Immunogen

Human recombit protein fragment corresponding to amino acids 1-375 of human PPM1D produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI3E1

Conjugate

Unconjugated

Gene

PPM1D

Gene Alias

IDDGIP, PP2C-DELTA, WIP1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8493

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases
  • PP2C family members are known to be negative regulators of cell stress response pathways
  • The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses
  • While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis
  • This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis
  • This gene is located in a chromosomal region known to be amplified in breast cancer
  • The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development.

Compare Similar Items

Show Difference

Img

OriGene

50-168-3886

--


Antigen:
PPM1D

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O15297

Gene Symbols:
PPM1D

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-375 of human PPM1D produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3E1

Conjugate:
Unconjugated

Gene:
PPM1D

Gene Alias:
IDDGIP, PP2C-DELTA, WIP1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8493

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3887

--


Antigen:
MSL2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9HCI7

Gene Symbols:
MSL2

Immunogen:
Full length human recombit protein of human MSL2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI3B11

Conjugate:
Unconjugated

Gene:
MSL2

Gene Alias:
MSL-2, MSL2L1, RNF184

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55167

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3888

--


Antigen:
KRT84

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9NSB2

Gene Symbols:
KRT84

Immunogen:
Full length human recombit protein of human KRT84 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI2D1

Conjugate:
Unconjugated

Gene:
KRT84

Gene Alias:
HB4, KRTHB4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3890

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-3890

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Antigen:
SMAP2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8WU79

Gene Symbols:
SMAP2

Immunogen:
Full length human recombit protein of human SMAP2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI9B6

Conjugate:
Unconjugated

Gene:
SMAP2

Gene Alias:
SMAP1L

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64744

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid