50-168-4141

SHARPIN Monoclonal Antibody (OTI1D11), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4141-Each-of-1 In Stock ₹ 43,217.21

50-168-4141 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

SHARPIN

Classification

Monoclonal

Conjugate

Unconjugated

Gene

SHARPIN

Gene Alias

SIPL1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

81858

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

OTI1D11

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q9H0F6

Gene Symbols

SHARPIN

Immunogen

Human recombit protein fragment corresponding to amino acids 1-326 of human SHARPIN produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
  • LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways
  • Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation
  • LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex
  • Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4141

--


Antigen:
SHARPIN

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
SHARPIN

Gene Alias:
SIPL1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
81858

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI1D11

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9H0F6

Gene Symbols:
SHARPIN

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-326 of human SHARPIN produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-4145

--


Antigen:
MAGEB2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MAGEB2

Gene Alias:
CT3.2, DAM6, MAGE-XP-2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4113

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI5C10

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O15479

Gene Symbols:
MAGEB2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-224 of human MAGEB2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-4146

--


Antigen:
IL20RA

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IL20RA

Gene Alias:
CRF2-8, IL-20R-alpha, IL-20R1, IL-20RA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
53832

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI7H7

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9UHF4

Gene Symbols:
IL20RA

Immunogen:
Human recombit protein fragment corresponding to amino acids 272-553 of human IL20RA produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-4147

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Antigen:
IFITM2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
IFITM2

Gene Alias:
1-8D, DSPA2c

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10581

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2B3

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q01629

Gene Symbols:
IFITM2

Immunogen:
Full length human recombit protein of human IFITM2 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a