50-168-4224

PDPN Monoclonal Antibody (OTI7B4), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4224-Each-of-1 In Stock ₹ 43,217.21

50-168-4224 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PDPN

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q86YL7

Gene Symbols

PDPN

Immunogen

Human recombit protein fragment corresponding to amino acids 23-131 of human PDPN produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI7B4

Conjugate

Unconjugated

Gene

PDPN

Gene Alias

AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10630

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight
  • Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs
  • Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells
  • As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes
  • Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential
  • Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue
  • Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells
  • Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC
  • Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm
  • Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4224

--


Antigen:
PDPN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q86YL7

Gene Symbols:
PDPN

Immunogen:
Human recombit protein fragment corresponding to amino acids 23-131 of human PDPN produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI7B4

Conjugate:
Unconjugated

Gene:
PDPN

Gene Alias:
AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10630

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4225

--


Antigen:
GPR17

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q13304

Gene Symbols:
GPR17

Immunogen:
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GPR17 C-terminal. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI10B8

Conjugate:
Unconjugated

Gene:
GPR17

Gene Alias:
G protein-coupled receptor 17

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2840

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4228

--


Antigen:
NRGN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q92686

Gene Symbols:
NRGN

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-78 of human NRGN produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1A2

Conjugate:
Unconjugated

Gene:
NRGN

Gene Alias:
RC3, hng

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4900

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4229

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Antigen:
RWDD3

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9Y3V2

Gene Symbols:
RWDD3

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-267 of human RWDD3 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI8B3

Conjugate:
Unconjugated

Gene:
RWDD3

Gene Alias:
RSUME

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25950

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid