50-168-4183

PDPN Monoclonal Antibody (OTI3H5), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4183-Each-of-1 In Stock ₹ 43,217.21

50-168-4183 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

PDPN

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PDPN

Gene Alias

AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10630

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

OTI3H5

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q86YL7

Gene Symbols

PDPN

Immunogen

Human recombit protein fragment corresponding to amino acids 23-131 of human PDPN produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight
  • Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs
  • Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells
  • As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes
  • Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential
  • Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue
  • Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells
  • Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC
  • Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm
  • Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.

Compare Similar Items

Show Difference

Img

OriGene

50-168-4183

--


Antigen:
PDPN

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDPN

Gene Alias:
AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10630

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI3H5

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q86YL7

Gene Symbols:
PDPN

Immunogen:
Human recombit protein fragment corresponding to amino acids 23-131 of human PDPN produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-4184

--


Antigen:
GPR26

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Gpr26

Gene Alias:
G protein-coupled receptor 26

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
192153, 233919

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI2F3

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8BZA7, Q9QXI3

Gene Symbols:
Gpr26

Immunogen:
Synthetic peptide

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-4185

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Antigen:
PDE3B

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PDE3B

Gene Alias:
HcGIP1, cGIPDE1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5140

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI3F5

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q13370

Gene Symbols:
PDE3B

Immunogen:
Human recombit protein fragment corresponding to amino acids 654-1073 of human PDE3B produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-4186

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Antigen:
E2F4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
E2F4

Gene Alias:
E2F-4

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1874

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
OTI10E7

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q16254

Gene Symbols:
E2F4

Immunogen:
Human recombit protein fragment corresponding to amino acids 86-413 of human E2F4 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1