50-168-4240

MBD1 Monoclonal Antibody (OTI2D7), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4240-Each-of-1 In Stock ₹ 43,217.21

50-168-4240 - Each of 1

₹ 43,217.21

In Stock

Quantity

1

Base Price: ₹ 43,217.21

GST (18%): ₹ 7,779.098

Total Price: ₹ 50,996.308

Antigen

MBD1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q9UIS9

Gene Symbols

MBD1

Immunogen

Human recombit protein fragment corresponding to amino acids 222-556 of human MBD1 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI2D7

Conjugate

Unconjugated

Gene

MBD1

Gene Alias

CXXC3, PCM1, RFT

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4152

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Methyl-CpG-binding domain protein 1 (MBD1) is a member of a family of mammalian proteins that specifically bind methylated regions of DNA
  • It is a transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides
  • Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS)
  • MBD1 acts as a transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1
  • Isoform 1 and isoform 2 can also repress transcription form unmethylated promoters.

Compare Similar Items

Show Difference

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OriGene

50-168-4240

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Antigen:
MBD1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9UIS9

Gene Symbols:
MBD1

Immunogen:
Human recombit protein fragment corresponding to amino acids 222-556 of human MBD1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI2D7

Conjugate:
Unconjugated

Gene:
MBD1

Gene Alias:
CXXC3, PCM1, RFT

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4152

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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OriGene

50-168-4243

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Antigen:
TNFSF10

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P50591

Gene Symbols:
TNFSF10

Immunogen:
Human recombit protein fragment corresponding to amino acids 39-281 of human TNFSF10 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
OTI12E12

Conjugate:
Unconjugated

Gene:
TNFSF10

Gene Alias:
APO2L, Apo-2L, CD253, TL2, TNLG6A, TRAIL

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8743

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

OriGene

50-168-4247

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Antigen:
IDE

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P14735, P35559

Gene Symbols:
IDE

Immunogen:
Human recombit protein fragment corresponding to amino acids 800-1019 of human IDE produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
OTI4E5

Conjugate:
Unconjugated

Gene:
IDE

Gene Alias:
INSULYSIN

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25700, 3416

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

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Antigen:
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Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q969K4

Gene Symbols:
ABTB1

Immunogen:
Full length human recombit protein of human ABTB1 produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI3G8

Conjugate:
Unconjugated

Gene:
ABTB1

Gene Alias:
BPOZ, BTB3, BTBD21, EF1ABP, PP2259

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80325

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid