50-168-4631
NEDD4 Monoclonal Antibody (OTI5F8), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-4631-Each-of-1 | In Stock | ₹ 43,217.21 |
50-168-4631 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,217.21
GST (18%): ₹ 7,779.098
Total Price: ₹ 50,996.308
Antigen
NEDD4
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P46934
Gene Symbols
NEDD4
Immunogen
Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
OTI5F8
Conjugate
Unconjugated
Gene
NEDD4
Gene Alias
NEDD4-1, RPF1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4734
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Description
- The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
- It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
- It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
- It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
- It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
- NEDD4 protein is localized to the sarcolemmal region of muscle fibers
- Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
- Hence it acts as down regulator of Notch-1 gene expression.
Compare Similar Items
Show Difference
Antigen: NEDD4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P46934
Gene Symbols: NEDD4
Immunogen: Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI5F8
Conjugate: Unconjugated
Gene: NEDD4
Gene Alias: NEDD4-1, RPF1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4734
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NEDD4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Immunogen:
Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI5F8
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
NEDD4-1, RPF1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4734
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NEDD4
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P46934
Gene Symbols: NEDD4
Immunogen: Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Western Blot
Clone: OTI6E12
Conjugate: Unconjugated
Gene: NEDD4
Gene Alias: NEDD4-1, RPF1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4734
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NEDD4
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Immunogen:
Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
OTI6E12
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
NEDD4-1, RPF1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4734
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NEDD4
Classification: Monoclonal
Concentration: __
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P46934
Gene Symbols: NEDD4
Immunogen: Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Western Blot
Clone: OTI7A1
Conjugate: Unconjugated
Gene: NEDD4
Gene Alias: NEDD4-1, RPF1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4734
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NEDD4
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Immunogen:
Human recombit protein fragment corresponding to amino acids 160-460 of human NEDD4 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Western Blot
Clone:
OTI7A1
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
NEDD4-1, RPF1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4734
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: MTHFR
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P42898
Gene Symbols: MTHFR
Immunogen: Human recombit protein fragment corresponding to amino acids 1-230 of human MTHFR produced in E.coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: OTI4C5
Conjugate: Unconjugated
Gene: MTHFR
Gene Alias: methylenetetrahydrofolate reductase
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4524
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MTHFR
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P42898
Gene Symbols:
MTHFR
Immunogen:
Human recombit protein fragment corresponding to amino acids 1-230 of human MTHFR produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
OTI4C5
Conjugate:
Unconjugated
Gene:
MTHFR
Gene Alias:
methylenetetrahydrofolate reductase
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4524
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid