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50-168-4905

ERBB2 Mouse anti-Human, Mouse, Rat, Clone: UMAB36, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4905-Each-of-1 In Stock ₹ 54,529.10

50-168-4905 - Each of 1

₹ 54,529.10

In Stock

Quantity

1

Base Price: ₹ 54,529.10

GST (18%): ₹ 9,815.238

Total Price: ₹ 64,344.338

Antigen

ERBB2

Classification

Monoclonal

Concentration

0.5-1.0 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P04626, P06494, P70424

Gene Symbols

ERBB2

Immunogen

Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

UMAB36

Conjugate

Unconjugated

Gene

ERBB2

Gene Alias

CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13866, 2064, 24337

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • ErbB2 (Her2/neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR (epidermal growth factor receptor) family that regulates biological responses such as cell growth, differentiation, and tissue development
  • ErbB2 has no ligand binding domain of its own and cannot bind growth factors
  • However, ErbB2 does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase
  • Autophosphorylation of tyrosine 1139 on ErbB2 allows binding of Grb2 and the Src SH2 domain, which allows activation of the Ras, Raf, ERK1/2 and JAK/STAT signaling pathways, respectively
  • Alternative splicing of ErbB2 results in several transcript variants, some encoding different isoforms and others that have not been fully characterized
  • In humans, the gene encoding ERBB2 is present on chromosome 17
  • Amplification and/or overexpression of the ErbB2 gene has been reported in ovarian tumors, breast, lung and skin cancer.

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OriGene

50-168-4905

--

Antigen:
ERBB2
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04626, P06494, P70424
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB36
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13866, 2064, 24337
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-4906

--

Antigen:
ERBB2
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 8% trehalose and no preservative
Gene Accession No.:
P04626, P06494, P70424
Gene Symbols:
ERBB2
Immunogen:
Human recombit protein fragment corresponding to amino acids 676-1255 of human ERBB2 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone:
UMAB36
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13866, 2064, 24337
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized

Img

OriGene

50-168-4908

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Antigen:
XRCC1
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 8% trehalose and no preservative
Gene Accession No.:
P18887
Gene Symbols:
XRCC1
Immunogen:
Full length human recombit protein of human XRCC1 produced in HEK293T cell.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone:
UMAB40
Conjugate:
Unconjugated
Gene:
XRCC1
Gene Alias:
RCC, SCAR26
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7515
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized

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OriGene

50-168-4909

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Antigen:
BMP4
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P12644
Gene Symbols:
BMP4
Immunogen:
Recombit fragment expressed in E.coli corresponding to amino acids 293-408 of human BMP4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB42
Conjugate:
Unconjugated
Gene:
BMP4
Gene Alias:
BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
652
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid