50-168-5047
CD2 Mouse anti-Human, Clone: UMAB6, liquid, UltraMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-5047-Each-of-1 | In Stock | ₹ 22,040.26 |
50-168-5047 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,040.26
GST (18%): ₹ 3,967.247
Total Price: ₹ 26,007.507
Antigen
CD2
Classification
Monoclonal
Concentration
0.5-1.0 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P06729
Gene Symbols
CD2
Immunogen
Protein expressed in 293T cell transfected with human CD2 expression vector
Quantity
30 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
UMAB6
Conjugate
Unconjugated
Gene
CD2
Gene Alias
LFA-2, SRBC, T11
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
914
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
- CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
- Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
- The interaction betwee CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
- Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
- Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
- Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
- CD2 deficiency reduces intestinal inflammation and helps to control infection
- Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.
Compare Similar Items
Show Difference
Antigen: CD2
Classification: Monoclonal
Concentration: 0.5-1.0 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P06729
Gene Symbols: CD2
Immunogen: Protein expressed in 293T cell transfected with human CD2 expression vector
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: UMAB6
Conjugate: Unconjugated
Gene: CD2
Gene Alias: LFA-2, SRBC, T11
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 914
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CD2
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P06729
Gene Symbols:
CD2
Immunogen:
Protein expressed in 293T cell transfected with human CD2 expression vector
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
UMAB6
Conjugate:
Unconjugated
Gene:
CD2
Gene Alias:
LFA-2, SRBC, T11
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
914
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: BUB1B
Classification: Monoclonal
Concentration: 0.5-1.0 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: O60566
Gene Symbols: BUB1B
Immunogen: Protein expressed in 293T cell transfected with human BUB1B expression vector
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: UMAB7
Conjugate: Unconjugated
Gene: BUB1B
Gene Alias: BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 701
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BUB1B
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
O60566
Gene Symbols:
BUB1B
Immunogen:
Protein expressed in 293T cell transfected with human BUB1B expression vector
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB7
Conjugate:
Unconjugated
Gene:
BUB1B
Gene Alias:
BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
701
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ERCC1
Classification: Monoclonal
Concentration: 0.5-1.0 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P07992
Gene Symbols: ERCC1
Immunogen: Protein expressed in 293T cell transfected with human ERCC1 expression vector
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 4F9
Conjugate: Unconjugated
Gene: ERCC1
Gene Alias: COFS4, RAD10, UV20
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2067
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ERCC1
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P07992
Gene Symbols:
ERCC1
Immunogen:
Protein expressed in 293T cell transfected with human ERCC1 expression vector
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
4F9
Conjugate:
Unconjugated
Gene:
ERCC1
Gene Alias:
COFS4, RAD10, UV20
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2067
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: HP
Classification: Monoclonal
Concentration: 0.5-1.0 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P00738
Gene Symbols: HP
Immunogen: Full length human recombit protein of human HP produced in HEK293T cell.
Quantity: 30 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: UMAB10
Conjugate: Unconjugated
Gene: HP
Gene Alias: BP, HP2ALPHA2, HPA1S
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3240
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
HP
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P00738
Gene Symbols:
HP
Immunogen:
Full length human recombit protein of human HP produced in HEK293T cell.
Quantity:
30 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
UMAB10
Conjugate:
Unconjugated
Gene:
HP
Gene Alias:
BP, HP2ALPHA2, HPA1S
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3240
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid