50-168-5359

BCL2 Mouse anti-Human, Clone: UMAB225, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5359-Each-of-1 In Stock ₹ 54,529.10

50-168-5359 - Each of 1

₹ 54,529.10

In Stock

Quantity

1

Base Price: ₹ 54,529.10

GST (18%): ₹ 9,815.238

Total Price: ₹ 64,344.338

Antigen

BCL2

Classification

Monoclonal

Conjugate

Unconjugated

Gene

BCL2

Gene Alias

Bcl-2, PPP1R50

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

596

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

UMAB225

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P10415

Gene Symbols

BCL2

Immunogen

Full length human recombit protein of human BCL2 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Related Products

Img

OriGene

50-168-5360

--

Img

OriGene

50-168-5467

--

Img

OriGene

50-168-5326

--

Img

OriGene

50-168-5503

--

Img

OriGene

50-168-5543

--

Img

OriGene

50-168-5548

--

Img

OriGene

50-168-5407

--

Img

OriGene

50-168-5393

--

Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5359

--


Antigen:
BCL2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BCL2

Gene Alias:
Bcl-2, PPP1R50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB225

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P10415

Gene Symbols:
BCL2

Immunogen:
Full length human recombit protein of human BCL2 produced in HEK293T cell.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-5360

--


Antigen:
BCL2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
BCL2

Gene Alias:
Bcl-2, PPP1R50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB225

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
P10415

Gene Symbols:
BCL2

Immunogen:
Full length human recombit protein of human BCL2 produced in HEK293T cell.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-5362

--


Antigen:
ALK

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
CD246, NBLST3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1A4

Formulation:
PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.:
Q9UM73

Gene Symbols:
ALK

Immunogen:
Human recombit protein fragment corresponding to amino acids 1300-1620 of human ALK produced in E.coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-5363

--


Antigen:
TYMS

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TYMS

Gene Alias:
HST422, TMS, TS

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7298

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB227

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P04818

Gene Symbols:
TYMS

Immunogen:
Full length human recombit protein of human TYMS (TS) produced in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a