50-168-5503

MCAM Mouse anti-Human, Clone: UMAB155, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5503-Each-of-1 In Stock ₹ 22,040.26

50-168-5503 - Each of 1

₹ 22,040.26

In Stock

Quantity

1

Base Price: ₹ 22,040.26

GST (18%): ₹ 3,967.247

Total Price: ₹ 26,007.507

Antigen

MCAM

Classification

Monoclonal

Conjugate

Unconjugated

Gene

MCAM

Gene Alias

CD146, MUC18

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4162

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

UMAB155

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P43121

Gene Symbols

MCAM

Immunogen

Full length human recombit protein of human MCAM produced in HEK293T cell.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily
  • CD146 is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and maligt cell types
  • In addition to its recognized role as a calcium-independent cell adhesion molecule, CD146 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly
  • CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue
  • CD146 expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread
  • Further, CD146 could be an adhesion molecule active in neural crest cells during embryonic development
  • CD146 acts also as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5503

--


Antigen:
MCAM

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MCAM

Gene Alias:
CD146, MUC18

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4162

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB155

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P43121

Gene Symbols:
MCAM

Immunogen:
Full length human recombit protein of human MCAM produced in HEK293T cell.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

OriGene

50-168-5505

--


Antigen:
VIM

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VIM

Gene Alias:
vimentin

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7431

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB159

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08670

Gene Symbols:
VIM

Immunogen:
Human recombit protein fragment corresponding to amino acids 210-466 of human VIM produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5506

--


Antigen:
VIM

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
VIM

Gene Alias:
vimentin

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7431, 81818

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB160

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P08670, P31000

Gene Symbols:
VIM

Immunogen:
Full length human recombit protein of human VIM produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5509

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Antigen:
RRM1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
RRM1

Gene Alias:
R1, RIR1, RR1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6240

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB165

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P23921

Gene Symbols:
RRM1

Immunogen:
Human recombit protein fragment corresponding to amino acids 541-792 of human RRM1 produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1