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50-168-5415

CD40 Mouse anti-Human, Clone: UMAB255, liquid, UltraMAB™

Manufacturer: OriGene

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Pack Size SKU Availability Price
Each of 1 50-168-5415-Each-of-1 In Stock ₹ 54,529.10

50-168-5415 - Each of 1

₹ 54,529.10

In Stock

Quantity

1

Base Price: ₹ 54,529.10

GST (18%): ₹ 9,815.238

Total Price: ₹ 64,344.338

Antigen

CD40

Classification

Monoclonal

Concentration

0.5-1.0 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P25942

Gene Symbols

CD40

Immunogen

Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

UMAB255

Conjugate

Unconjugated

Gene

CD40

Gene Alias

Bp50, CDW40, TNFRSF5, p50

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

958

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The CD40 antigen is a single chain glycoprotein that is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin′s disease associated antigen, CD30
  • CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells
  • CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation
  • AT-hook transcription factor AKNA is reported to coordinately regulate the expression of CD40, which may be important for homotypic cell interactions
  • Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction
  • The interaction of CD40 and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis
  • Two alternatively spliced transcript variants of CD40 encoding distinct isoforms have been reported
  • Diseases associated with CD40 dysfunction include Type 3 Hyper-Igm immunodeficiency and CD40 ligand deficiency.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5415

--

Antigen:
CD40
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P25942
Gene Symbols:
CD40
Immunogen:
Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB255
Conjugate:
Unconjugated
Gene:
CD40
Gene Alias:
Bp50, CDW40, TNFRSF5, p50
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
958
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-5416

--

Antigen:
CD40
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P25942
Gene Symbols:
CD40
Immunogen:
Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone:
UMAB255
Conjugate:
Unconjugated
Gene:
CD40
Gene Alias:
Bp50, CDW40, TNFRSF5, p50
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
958
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized

Img

OriGene

50-168-5417

--

Antigen:
TNFRSF8
Classification:
Monoclonal
Concentration:
0.5-1.0 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P28908
Gene Symbols:
TNFRSF8
Immunogen:
Human recombit protein fragment corresponding to amino acids 408-595 of human TNFRSF8 produced in E.coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
UMAB256
Conjugate:
Unconjugated
Gene:
TNFRSF8
Gene Alias:
CD30, D1S166E, Ki-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
943
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid

Img

OriGene

50-168-5418

--

Antigen:
TNFRSF8
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.:
P28908
Gene Symbols:
TNFRSF8
Immunogen:
Human recombit protein fragment corresponding to amino acids 408-595 of human TNFRSF8 produced in E.coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Peptide Array, Western Blot
Clone:
UMAB256
Conjugate:
Unconjugated
Gene:
TNFRSF8
Gene Alias:
CD30, D1S166E, Ki-1
Host Species:
Mouse
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
943
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Lyophilized