50-168-5588

FOXP3 Mouse anti-Human, Clone: UMAB248, liquid, UltraMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-5588-Each-of-1 In Stock ₹ 22,040.26

50-168-5588 - Each of 1

₹ 22,040.26

In Stock

Quantity

1

Base Price: ₹ 22,040.26

GST (18%): ₹ 3,967.247

Total Price: ₹ 26,007.507

Antigen

FOXP3

Classification

Monoclonal

Conjugate

Unconjugated

Gene

FOXP3

Gene Alias

AIID, DIETER, IPEX, JM2, PIDX, XPID

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

50943

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Clone

UMAB248

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q9BZS1

Gene Symbols

FOXP3

Immunogen

Full length human recombit protein of human FOXP3 produced in E.coli.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Related Products

Img

OriGene

50-168-5405

--

Img

OriGene

50-168-5406

--

Img

OriGene

50-168-5393

--

Img

OriGene

50-168-5351

--

Img

OriGene

50-168-5326

--

Img

OriGene

50-168-5298

--

Img

OriGene

50-168-5560

--

Img

OriGene

50-168-5568

--

Description

  • FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis
  • FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells
  • FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells
  • Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice
  • In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome
  • Transcript variants of FOXP3 encoding different isoforms have been identified
  • In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.

Compare Similar Items

Show Difference

Img

OriGene

50-168-5588

--


Antigen:
FOXP3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
FOXP3

Gene Alias:
AIID, DIETER, IPEX, JM2, PIDX, XPID

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50943

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB248

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9BZS1

Gene Symbols:
FOXP3

Immunogen:
Full length human recombit protein of human FOXP3 produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

OriGene

50-168-5593

--


Antigen:
CD40

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
Bp50, CDW40, TNFRSF5, p50

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB255

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P25942

Gene Symbols:
CD40

Immunogen:
Human recombit protein fragment corresponding to amino acids 21-166 of human CD40 produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5595

--


Antigen:
TYR

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TYR

Gene Alias:
ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7299

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
UMAB257

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P14679

Gene Symbols:
TYR

Immunogen:
Human recombit protein fragment corresponding to amino acids 19-320 of human TYR produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

OriGene

50-168-5597

--


Antigen:
MSH2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
MSH2

Gene Alias:
COCA1, FCC1, HNPCC, HNPCC1, LCFS2

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4436

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
UMAB259

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P43246

Gene Symbols:
MSH2

Immunogen:
Human recombit protein fragment corresponding to amino acids 1-304 of human MSH2 produced in E.coli.

Quantity:
30 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b