50-172-7451

PTPN22 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-172-7451-Each-of-1 In Stock ₹ 42,443.75

50-172-7451 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

PTPN22

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPN22

Gene Alias

Lymphoid phosphatase, LYP, LYP1, LYP2, PEP, PTPN22, PTPN8

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19260, 26191, 295338

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.24 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P29352, Q9Y2R2

Gene Symbols

Ptpn22

Immunogen

PTPN22 Fusion Protein Ag2397

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The protein tyrosine phosphatase PTPN22 (PTP22, LYP, PEP, formerly PTPN8) is a genetic variant that confers risk of developing diverse human autoimmune diseases such as type 1 diabetes and rheumatoid arthritis
  • The minor allele of a missense SNP in PTPN22 encodes a hematopoietic-specific protein tyrosine phosphatase also known as ""Lyp."" The risk allele is present in about 17% of Caucasian individuals from the general population and in approximately 28% of Caucasian individuals with rheumatoid arthritis; it is thought to disrupt the P1 proline-rich motif that is important for interaction with the Src homology-3 (SH3) domain of CSK (cytoplasmic tyrosine kinase), potentially altering the normal functions of these proteins as negative regulators of T cell activation
  • The interaction between CSK and PTPN22 is highly specific and it is speculated that PTPN22 may be an effector and/or regulator of CSK in T cells and other hematopoietic cells.

Compare Similar Items

Show Difference

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Proteintech Group Inc

50-172-7451

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Antigen:
PTPN22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN22

Gene Alias:
Lymphoid phosphatase, LYP, LYP1, LYP2, PEP, PTPN22, PTPN8

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19260, 26191, 295338

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.24 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P29352, Q9Y2R2

Gene Symbols:
Ptpn22

Immunogen:
PTPN22 Fusion Protein Ag2397

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7452

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Antigen:
LY96/MD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LY96

Gene Alias:
ESOP 1, ESOP1, Ly 96, LY96, lymphocyte antigen 96, MD 2, MD2, Protein MD 2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23643

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q9Y6Y9

Gene Symbols:
LY96

Immunogen:
LY96/MD2 Fusion Protein Ag2447

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7454

--


Antigen:
MPZL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MPZL2

Gene Alias:
Epithelial V like antigen 1, EVA, EVA1, MPZL2, myelin protein zero like 2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10205, 14012, 300679

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.31 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O60487, O70255

Gene Symbols:
MPZL2

Immunogen:
MPZL2 Fusion Protein Ag2419

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-172-7455

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Antigen:
PRIM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRIM2

Gene Alias:
DNA primase 58 kDa subunit, DNA primase large subunit, p58, PRIM2, PRIM2A

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19076, 301323, 5558

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
O89044, P33610, P49643

Gene Symbols:
Prim2

Immunogen:
PRIM2 Fusion Protein Ag2370

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG