50-173-0178

beta Arrestin 1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Each of 1 50-173-0178-Each-of-1 In Stock ₹ 42,443.75

50-173-0178 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

beta Arrestin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARRB1

Gene Alias

ARB1, ARR1, ARRB1, Arrestin beta 1, arrestin, beta 1, Beta arrestin 1, beta-Arrestin-1

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

109689, 408

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.13 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P49407, Q8BWG8

Gene Symbols

ARRB1

Immunogen

beta Arrestin 1 Fusion Protein Ag7608

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system
  • Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor)
  • After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G-protein receptor kinases (GRKs) on serine residues
  • Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane
  • Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.

Compare Similar Items

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Proteintech Group Inc

50-173-0178

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Antigen:
beta Arrestin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARRB1

Gene Alias:
ARB1, ARR1, ARRB1, Arrestin beta 1, arrestin, beta 1, Beta arrestin 1, beta-Arrestin-1

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109689, 408

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P49407, Q8BWG8

Gene Symbols:
ARRB1

Immunogen:
beta Arrestin 1 Fusion Protein Ag7608

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0180

--


Antigen:
ICAM-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ICAM1

Gene Alias:
BB2, CD54, ICAM 1, ICAM1, P3.58

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3383

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.31 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P05362

Gene Symbols:
ICAM1

Immunogen:
ICAM-1 Fusion Protein Ag8309

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0182

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Antigen:
RIPK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIPK2

Gene Alias:
CARD3, CARDIAK, CCK, GIG30, Receptor interacting protein 2, RICK, RIP 2, RIP2, RIPK2

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
192656, 362491, 8767

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O43353, P58801

Gene Symbols:
Ripk2

Immunogen:
RIPK2 Fusion Protein Ag0909

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Proteintech Group Inc

50-173-0183

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Antigen:
COX8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COX8A

Gene Alias:
COX, COX8, COX8 2, COX8A, COX8L, VIII, VIII L

Host Species:
Rabbit

Purification Method:
Antigen Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12868, 1351

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P10176, Q64445

Gene Symbols:
COX8A

Immunogen:
COX8A Fusion Protein Ag2885

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG