50-173-6922

TAU Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1E9A8, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-6922-Each-of-1 In Stock ₹ 42,443.75

50-173-6922 - Each of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

TAU

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P10636, P10637, P19332

Gene Symbols

Mapt

Immunogen

TAU Fusion Protein Ag21926

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgG2c

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

1E9A8

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

DDPAC, FTDP 17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PPND, TAU

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100738351, 17762, 29477, 4137

Content And Storage

-20°C

Form

Liquid

Description

  • Tau is a neuronal microtubule-associated protein found predomitly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer′s diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclindependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Compare Similar Items

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Img

Proteintech Group Inc

50-173-6922

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Antigen:
TAU

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P10636, P10637, P19332

Gene Symbols:
Mapt

Immunogen:
TAU Fusion Protein Ag21926

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG2c

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
1E9A8

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
DDPAC, FTDP 17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PPND, TAU

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100738351, 17762, 29477, 4137

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6923

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Antigen:
TAZ

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
Q9EPK5, Q9GZV5

Gene Symbols:
Wwtr1

Immunogen:
TAZ Fusion Protein Ag13330

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2A12A10

Conjugate:
Unconjugated

Gene:
WWTR1

Gene Alias:
TAZ, WWTR1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25937, 295062, 97064

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6927

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Antigen:
MDH1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
P14152, P40925

Gene Symbols:
Mdh1

Immunogen:
MDH1 Fusion Protein Ag8744

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
1F9A2

Conjugate:
Unconjugated

Gene:
MDH1

Gene Alias:
Cytosolic malate dehydrogenase, MDH s, MDH1, MDHA, MOR2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
17449, 4190

Content And Storage:
-20°C

Form:
Liquid

Img

Proteintech Group Inc

50-173-6929

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Antigen:
CNOT1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.:
A5YKK6

Gene Symbols:
CNOT1

Immunogen:
CNOT1 Fusion Protein Ag5623

Quantity:
150 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
1A10A11

Conjugate:
Unconjugated

Gene:
CNOT1

Gene Alias:
AD 005, CCR4 associated factor 1, CDC39, CNOT1, hNOT1, KIAA1007, NOT1, NOT1H

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
23019

Content And Storage:
-20°C

Form:
Liquid