50-194-3816
TNF alpha Polyclonal Antibody, Rockland™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-194-3816-Each-of-1 | In Stock | ₹ 1,24,459.00 |
50-194-3816 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,24,459.00
GST (18%): ₹ 22,402.62
Total Price: ₹ 1,46,861.62
Antigen
TNF alpha
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Tnf
Gene Alias
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species
Rabbit
Quantity
1 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Accession No.
P01375
Gene Symbols
Tnf
Immunogen
TNF alpha antibody used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human TNFalpha.
Regulatory Status
RUO
Gene ID (Entrez)
7124
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody is primarily directed against mature 17,000 MW human TNF alpha and is useful in determining its presence in various assays
- In general, this antibody also detects primate TNF alpha in the same formats using similar dilutions
- The antibody does not recognize human TNF beta (lymphotoxin)
- This IgG fraction antibody will recognize the cell-bound precursor of TNF alpha as a 26,000 protein in immunoblots, particularly in denatured samples
- This antibody is also useful for neutralization of human and primate TNF alpha activity in bioassays
- It does not neutralize the biological activity of lymphotoxin
- For neutralization, it is recommended to incubate the sample with a 1:200 dilution of the antibody for at least 4 hours before being tested
- A control of similarly diluted normal rabbit IgG is recommended
- TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
- This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
- TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
- TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
- Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
- Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
- TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
- This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
Compare Similar Items
Show Difference
Antigen: TNF alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tnf
Gene Alias: APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species: Rabbit
Quantity: 1 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Accession No.: P01375
Gene Symbols: Tnf
Immunogen: TNF alpha antibody used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human TNFalpha.
Regulatory Status: RUO
Gene ID (Entrez): 7124
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TNF alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tnf
Gene Alias:
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Host Species:
Rabbit
Quantity:
1 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Accession No.:
P01375
Gene Symbols:
Tnf
Immunogen:
TNF alpha antibody used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human TNFalpha.
Regulatory Status:
RUO
Gene ID (Entrez):
7124
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: VEGF-165
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VEGFA
Gene Alias: angiogenic factor; BOS_21465; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; VAS; vascular endothelial growth factor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; Vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; Vascular permeability factor; Vasculotropin; vegf; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Applications: ELISA, Western Blot
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Accession No.: P15692
Gene Symbols: VEGFA
Immunogen: This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human VEGF-165 protein.
Regulatory Status: RUO
Gene ID (Entrez): 7422
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Antigen:
VEGF-165
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VEGFA
Gene Alias:
angiogenic factor; BOS_21465; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; VAS; vascular endothelial growth factor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; Vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; Vascular permeability factor; Vasculotropin; vegf; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Applications:
ELISA, Western Blot
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Accession No.:
P15692
Gene Symbols:
VEGFA
Immunogen:
This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human VEGF-165 protein.
Regulatory Status:
RUO
Gene ID (Entrez):
7422
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Antigen: IDO1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: Ido1
Gene Alias: EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P28776
Gene Symbols: Ido1
Immunogen: IDO1 antibody was produced in mouse by repeated immunizations with mouse recombinant IDO1 protein followed by hybridoma development.
Regulatory Status: RUO
Gene ID (Entrez): 15930
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
IDO1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
Ido1
Gene Alias:
EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Applications:
ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P28776
Gene Symbols:
Ido1
Immunogen:
IDO1 antibody was produced in mouse by repeated immunizations with mouse recombinant IDO1 protein followed by hybridoma development.
Regulatory Status:
RUO
Gene ID (Entrez):
15930
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: IL-6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Il6
Gene Alias: B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BOS_4106; BSF2; BSF-2; CDF; ChIL-6; CTL differentiation factor; EGM_12696; HGF; H-IL-6; HSF; Hybridoma growth factor; hypothetical protein; IFNB2; IFN-beta-2; IL6; Il-6; ILg6; ILN; Interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin BSF-2; Interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 protein; M-IL-6; R-IL-6
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Accession No.: P08505
Gene Symbols: Il6
Immunogen: Anti-IL-6 is an IgG fraction antibody prepared from rabbit antiserum after repeated immunizations with recombinant mouse IL-6 protein produced in E.coli.
Regulatory Status: RUO
Gene ID (Entrez): 16193
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Antigen:
IL-6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Il6
Gene Alias:
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BOS_4106; BSF2; BSF-2; CDF; ChIL-6; CTL differentiation factor; EGM_12696; HGF; H-IL-6; HSF; Hybridoma growth factor; hypothetical protein; IFNB2; IFN-beta-2; IL6; Il-6; ILg6; ILN; Interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin BSF-2; Interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 protein; M-IL-6; R-IL-6
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Accession No.:
P08505
Gene Symbols:
Il6
Immunogen:
Anti-IL-6 is an IgG fraction antibody prepared from rabbit antiserum after repeated immunizations with recombinant mouse IL-6 protein produced in E.coli.
Regulatory Status:
RUO
Gene ID (Entrez):
16193
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized