50-194-3847
Phospho-IRS1 (Ser307)Rabbit anti-Human, Polyclonal, Rockland™
Manufacturer: Rockland Immunochemicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-194-3847-Each-of-1 | In Stock | ₹ 52,930.08 |
50-194-3847 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,930.08
GST (18%): ₹ 9,527.414
Total Price: ₹ 62,457.494
Antigen
Phospho-IRS1 (Ser307)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRS1
Gene Alias
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; Irs-1; IRS1IRM; pp185
Host Species
Rabbit
Regulatory Status
RUO
Gene ID (Entrez)
3667
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
P35568
Gene Symbols
IRS1
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This affinity-purified antibody is directed against the phosphorylated form of human IRS1 protein at the pS307 residue
- Reactivity occurs against human IRS1 pS307 protein and the antibody is specific for the phosphorylated form of the protein
- Reactivity with non-phosphorylated human IRS1 is minimal by ELISA
- A BLAST analysis was used to suggest cross reactivity with IRS1 from human, mouse, rat, dog and vervet monkey based on 100% homology with the immunizing sequence
- Partial reactivity is also expected against IRS1 from pig (94%), bovine (94%) and chicken (88%) sources
- Reactivity of this antibody with IRS1 from other species is unknown
- IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
- IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
- An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
- Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
- Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
- IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.
Compare Similar Items
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Antigen: Phospho-IRS1 (Ser307)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRS1
Gene Alias: G972R; HIRS-1; Insulin receptor substrate 1; IRS1; Irs-1; IRS1IRM; pp185
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 3667
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P35568
Gene Symbols: IRS1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Antigen:
Phospho-IRS1 (Ser307)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRS1
Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; Irs-1; IRS1IRM; pp185
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
3667
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P35568
Gene Symbols:
IRS1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Antigen: DNMT3L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNMT3L
Gene Alias: cytosine-5-methyltransferase 3-like protein; D6Ertd14e; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; DNA methyltransferase 3 like; Dnmt 3L; DNMT3L; ecat7; human cytosine-5-methyltransferase 3-like protein; MGC1090
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 29947
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 1.11 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q9UJW3
Gene Symbols: DNMT3L
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Antigen:
DNMT3L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNMT3L
Gene Alias:
cytosine-5-methyltransferase 3-like protein; D6Ertd14e; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; DNA methyltransferase 3 like; Dnmt 3L; DNMT3L; ecat7; human cytosine-5-methyltransferase 3-like protein; MGC1090
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
29947
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
1.11 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q9UJW3
Gene Symbols:
DNMT3L
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Antigen: SFRP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SFRP1
Gene Alias: 2210415K03Rik; AW011917; AW107218; AW742929; frizzled-related protein; FRP; FRP1; FRP-1; FrzA; SARP2; SARP-2; Secreted apoptosis-related protein 2; secreted frizzled related protein 1; Secreted frizzled-related protein 1; secreted frizzled-related sequence protein 1; Sfrp1; sFRP-1
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 20377, 6422
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q8C4U3, Q8N474
Gene Symbols: SFRP1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Antigen:
SFRP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SFRP1
Gene Alias:
2210415K03Rik; AW011917; AW107218; AW742929; frizzled-related protein; FRP; FRP1; FRP-1; FrzA; SARP2; SARP-2; Secreted apoptosis-related protein 2; secreted frizzled related protein 1; Secreted frizzled-related protein 1; secreted frizzled-related sequence protein 1; Sfrp1; sFRP-1
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
20377, 6422
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q8C4U3, Q8N474
Gene Symbols:
SFRP1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Antigen: HAUSP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: USP7
Gene Alias: 2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; Deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; Herpesvirus-associated ubiquitin-specific protease; mHAUSP; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); Ubiquitin thioesterase 7; ubiquitin thiolesterase 7; Ubiquitin-specific-processing protease 7; UBP; USP7
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 7874
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunoprecipitation, Western Blot
Concentration: 1.1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q93009
Gene Symbols: USP7
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Antigen:
HAUSP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
USP7
Gene Alias:
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; Deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; Herpesvirus-associated ubiquitin-specific protease; mHAUSP; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); Ubiquitin thioesterase 7; ubiquitin thiolesterase 7; Ubiquitin-specific-processing protease 7; UBP; USP7
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
7874
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunoprecipitation, Western Blot
Concentration:
1.1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q93009
Gene Symbols:
USP7
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody