50-198-0745

TLR2 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-0745-Each-of-1 In Stock ₹ 36,897.75

50-198-0745 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

TLR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tlr2

Gene Alias

CD282; Ly105; TIL4; Tlr2; toll like receptor 2; Toll/interleukin-1 receptor-like protein 4; Toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7097

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O60603

Gene Symbols

Tlr2

Immunogen

KLH conjugated synthetic peptide derived from human TLR2 (cytoplasmic domain).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bioss

50-198-0898

--

Img

Bioss

50-198-0756

--

Img

Bioss

50-198-1445

--

Img

Bioss

50-198-1349

--

Img

Bioss

50-198-1350

--

Img

Bioss

50-198-0566

--

Img

Bioss

50-198-1076

--

Img

Bioss

50-198-1434

--

Description

  • TLR2 is a member of the Toll-like receptor (TLR) family which play a fundamental role in pathogen recognition and activation of innate immunity
  • TLR proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappa-B
  • TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer, can recognize a variety of bacterial and mycoplasma lipoproteins respectively
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • The various TLRs exhibit different patterns of expression
  • TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB
  • TLR2 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • Ten human homologs of TLRs (TLR1-10) have been described
  • TLR2 is expressed in human cells such as tonsils, microglia, lymph nodes, and appendices, activated B-cells in germinal centers
  • CD14+ monocytes express the highest level of TLR2 followed by CD15+ granulocytes, CD19+ B-cells, and CD3+ T-cells
  • The expression of TLR2 on different cell types are regulated by different immune response modifiers
  • For example, LPS, GM-CSF, IL-1, and IL-10 up regulates TLR2 whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.

Compare Similar Items

Show Difference

Img

Bioss

50-198-0745

--


Antigen:
TLR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tlr2

Gene Alias:
CD282; Ly105; TIL4; Tlr2; toll like receptor 2; Toll/interleukin-1 receptor-like protein 4; Toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7097

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O60603

Gene Symbols:
Tlr2

Immunogen:
KLH conjugated synthetic peptide derived from human TLR2 (cytoplasmic domain).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0746

--


Antigen:
Sclerostin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SOST

Gene Alias:
5430411E23Rik; CDD; DAND6; sclerosteosis; Sclerostin; Sost; SOST1; UNQ2976/PRO7455/PRO7476; VBCH

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
50964

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9BQB4

Gene Symbols:
SOST

Immunogen:
KLH conjugated synthetic peptide derived from human Sclerostin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0747

--


Antigen:
ADORA2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADORA2B

Gene Alias:
A2b; A2b receptor; A2b, Rs; A2BAR; A2BR; AA2BR; adenosine A2b receptor; Adenosine receptor A2b; ADORA2; Adora2b; AI480866; AI605384; HGNC:264; netrin-1 receptor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
136

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P29275

Gene Symbols:
ADORA2B

Immunogen:
KLH conjugated synthetic peptide derived from human ADORA2B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0748

--


Antigen:
RSV Nucleoprotein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
KLH conjugated synthetic peptide derived from human Respiratory Syncytial Virus Nucleoprotein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG