50-198-1349

MC4 Receptor Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-1349-Each-of-1 In Stock ₹ 36,897.75

50-198-1349 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

MC4 Receptor

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MC4R

Gene Alias

MC4; MC4 receptor; mc4r; MC4-R; melanocortin 4 receptor; Melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4160

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P32245

Gene Symbols

MC4R

Immunogen

KLH conjugated synthetic peptide derived from human MC4 Receptor .

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Expression of MC4R has been reported in brain
  • Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This 'turn-off' activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

Img

Bioss

50-198-1349

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Antigen:
MC4 Receptor

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MC4R

Gene Alias:
MC4; MC4 receptor; mc4r; MC4-R; melanocortin 4 receptor; Melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4160

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P32245

Gene Symbols:
MC4R

Immunogen:
KLH conjugated synthetic peptide derived from human MC4 Receptor .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1350

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Antigen:
MC5 Receptor/MC5-R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MC5R

Gene Alias:
H MC2; MC2; MC-2; MC5; MC5 receptor; Mc5r; MC5-R; melanocortin 5 receptor; Melanocortin receptor 5; melanocortin-5 receptor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4161

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P33032

Gene Symbols:
MC5R

Immunogen:
KLH conjugated synthetic peptide derived from human MC5 Receptor.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1351

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Antigen:
MRAP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MRAP2

Gene Alias:
bA51G5.2; BB633055; BMIQ18; C6orf117; MC2R accessory protein 2; melanocortin 2 receptor accessory protein 2; Melanocortin-2 receptor accessory protein 2; MRAP2; RGD1309873

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
112609

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q96G30

Gene Symbols:
MRAP2

Immunogen:
KLH conjugated synthetic peptide derived from human MRAP2 (81-130aa).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1352

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Antigen:
STAT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT3

Gene Alias:
1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6774

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P40763

Gene Symbols:
STAT3

Immunogen:
KLH conjugated synthetic peptide derived from human STAT3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG