50-198-1272

PTPN5/STEP Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-1272-Each-of-1 In Stock ₹ 36,897.75

50-198-1272 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

PTPN5/STEP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPN5

Gene Alias

FLJ14427; Neural-specific protein-tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 5; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); protein-tyrosine phosphatase striatum-enriched; protein-tyrosine-phosphatase non-receptor 5; PTN5; PTP STEP; PTPN 5; Ptpn5; PTPSTEP; STEP; STEP61; striatal-enriched protein tyrosine phosphatase; Striatum-enriched protein-tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

84867

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P54829

Gene Symbols

PTPN5

Immunogen

KLH conjugated synthetic peptide derived from human PTPN5.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reversible phosphorylation of tyrosine residues is a key regulatory mechanism for numerous cellular events such as proliferation, differentiation, gene expression and migration
  • Abnormalities in tyrosine phosphorylation play a role in the pathogenesis of numerous inherited or acquired human diseases from cancer to immune deficiencies
  • There are at least 107 genes coding for PTPs (protein tyrosine phosphatases) in the human genome
  • All known PTPs contain a highly conserved 12 amino acid catalytic domain and are further distinguished on the basis of additional structural motifs
  • The receptor-like PTPs exhibit an extracellular domain, a single transmembrane and one or two intracellular phosphatase domains
  • The nonreceptor cytoplasmic PTPs contain a single phosphatase domain and additional amino acid sequences that are homologous to motifs found in other classes of proteins
  • Protein tyrosine phosphatases PTPN5 (STEP), PTPRR and PTPN7 comprise a family of phosphatases that specifically inactivate MAPKs (mitogen-activated protein kinases)
  • There are multiple forms of STEP in the adult rat brain which show differential enrichment in brain regions implicated in aspects of cognitive, affective, and motor behaviors
  • Some of the STEP isoforms are generated through alternative splicing of a single STEP gene and each has unique intracellular targets and functions.

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Img

Bioss

50-198-1272

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Antigen:
PTPN5/STEP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN5

Gene Alias:
FLJ14427; Neural-specific protein-tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 5; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); protein-tyrosine phosphatase striatum-enriched; protein-tyrosine-phosphatase non-receptor 5; PTN5; PTP STEP; PTPN 5; Ptpn5; PTPSTEP; STEP; STEP61; striatal-enriched protein tyrosine phosphatase; Striatum-enriched protein-tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
84867

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P54829

Gene Symbols:
PTPN5

Immunogen:
KLH conjugated synthetic peptide derived from human PTPN5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1274

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Antigen:
SORCS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Sorcs1

Gene Alias:
FLJ41758; FLJ43475; FLJ44957; hSorCS; mSorCS; SORCS; SORCS receptor 1; SORCS1; sortilin related VPS10 domain containing receptor 1; sortilin-related VPS10 domain containing receptor 1; VPS10 domain receptor protein SORCS 1; VPS10 domain-containing receptor SorCS1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
114815

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8WY21

Gene Symbols:
Sorcs1

Immunogen:
KLH conjugated synthetic peptide derived from human SORCS1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1275

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Antigen:
CNG channel beta 1/truncated GARP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNGB1

Gene Alias:
CNCG2; CNCG3L; CNCG4; CNG channel 4; CNG channel beta-1; CNG4; CNG-4; CNGB1; CNGB1B; cyclic nucleotide gated channel beta 1; Cyclic nucleotide-gated cation channel 4; Cyclic nucleotide-gated cation channel beta-1; Cyclic nucleotide-gated cation channel gamma; Cyclic nucleotide-gated cation channel modulatory subunit; cyclic nucleotide-gated channel beta subunit 1; Cyclic nucleotide-gated channel beta-1; GAR1; GARP; GARP2; Glutamic acid-rich protein; glutamic-acid-rich protein; Gm1959; RCNC2; RCNCb; RCNCbeta; RP45

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1258

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q14028

Gene Symbols:
CNGB1

Immunogen:
KLH conjugated synthetic peptide derived from human truncated GARP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1276

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Antigen:
SNAP91/AP180

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Snap91

Gene Alias:
91 kDa synaptosomal-associated protein; 91kDa; Ap180; assembly protein 180 (AP180); assembly protein, 180kDa; CALM; Clathrin coat assembly protein AP180; Clathrin coat-associated protein AP180; F1-20; KIAA0656; mKIAA0656; Phosphoprotein F1-20; Snap91; synaptosomal-associated protein 91; synaptosomal-associated protein 91 kDa; synaptosomal-associated protein, 91 kDa; synaptosomal-associated protein, 91kDa homolog; synaptosome associated protein 91; synaptosome associated protein 91kDa

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9892

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O60641

Gene Symbols:
Snap91

Immunogen:
KLH conjugated synthetic peptide derived from human AP180.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG