50-198-1451
TPIA2/PTPRN Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-1451-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-1451 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
TPIA2/PTPRN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPRN
Gene Alias
105 kDa islet cell antigen; BEM-3; Brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; Islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; PTPRN; Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5798
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q16849
Gene Symbols
PTPRN
Immunogen
KLH conjugated synthetic peptide derived from human TPIA2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- IA-2 (insulinoma-associated protein 2, ICA512, PTPRN) is a member of the transmembrane protein tyrosine phosphatase (PTP) family located in secretory granules of neuroendocrine cells
- The IA-2 protein is 979 amino acids in length and consists of a luminal domain, transmembrane domain, and cytoplasmic domain
- Although a member of the PTP family, IA-2 lacks phosphatase activity with known substrates due to amino acid substitutions at critical sites in its PTP domain
- Two paralog RPTPs, IA-2 and IA-2beta were identified as major autoantigens in type-1 diabetes mellitus
- On granule exocytosis, the IA-2 cytoplasmic domain is cleaved and the resulting cytosolic fragment moves into the nucleus where it enhances the levels of phosphorylated STAT5 and STAT3, thereby inducing insulin gene transcription and granule biogenesis
- IA-2 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.
Compare Similar Items
Show Difference
Antigen: TPIA2/PTPRN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPRN
Gene Alias: 105 kDa islet cell antigen; BEM-3; Brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; Islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; PTPRN; Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5798
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q16849
Gene Symbols: PTPRN
Immunogen: KLH conjugated synthetic peptide derived from human TPIA2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TPIA2/PTPRN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPRN
Gene Alias:
105 kDa islet cell antigen; BEM-3; Brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; Islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; PTPRN; Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5798
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q16849
Gene Symbols:
PTPRN
Immunogen:
KLH conjugated synthetic peptide derived from human TPIA2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Proprotein Convertase 2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pcsk2
Gene Alias: 6330411F23Rik; AI839700; BOS_12928; EC 3.4.21.94; KEX2-like endoprotease 2; NEC 2; Nec2; Nec-2; Neuroendocrine convertase 2; PC2; Pcsk2; Phpp-2; Prohormone convertase 2; Proprotein convertase 2; proprotein convertase subtilisin/kexin type 2; proprotein convertase type 2; Rpc2; SPC2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5126
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P16519
Gene Symbols: Pcsk2
Immunogen: KLH conjugated synthetic peptide derived from human Proprotein Convertase 2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Proprotein Convertase 2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pcsk2
Gene Alias:
6330411F23Rik; AI839700; BOS_12928; EC 3.4.21.94; KEX2-like endoprotease 2; NEC 2; Nec2; Nec-2; Neuroendocrine convertase 2; PC2; Pcsk2; Phpp-2; Prohormone convertase 2; Proprotein convertase 2; proprotein convertase subtilisin/kexin type 2; proprotein convertase type 2; Rpc2; SPC2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5126
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P16519
Gene Symbols:
Pcsk2
Immunogen:
KLH conjugated synthetic peptide derived from human Proprotein Convertase 2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: QRFP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: QRFP
Gene Alias: 26RFa; Neuropeptide RF-amide; Orexigenic neuropeptide QRFP; P518; P518 precursor protein; prepro-QRFP; Pyroglutamylated arginine-phenylalanine-amide peptide; pyroglutamylated RFamide peptide; QRF-amide; QRFP; RF(Arg-Phe)amide family 26 amino acid peptide (P518)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 347148
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P83859
Gene Symbols: QRFP
Immunogen: KLH conjugated synthetic peptide derived from human QRFP.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
QRFP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
QRFP
Gene Alias:
26RFa; Neuropeptide RF-amide; Orexigenic neuropeptide QRFP; P518; P518 precursor protein; prepro-QRFP; Pyroglutamylated arginine-phenylalanine-amide peptide; pyroglutamylated RFamide peptide; QRF-amide; QRFP; RF(Arg-Phe)amide family 26 amino acid peptide (P518)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
347148
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P83859
Gene Symbols:
QRFP
Immunogen:
KLH conjugated synthetic peptide derived from human QRFP.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TUB 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TUB
Gene Alias: CELE_F10B5.4; F10B5.4; Rd5; RDOB; retinal degeneration 5; Tub; tub-1; tubby bipartite transcription factor; tubby candidate gene; tubby homolog; tubby homolog (mouse); tubby homologue; Tubby protein; Tubby protein homolog; Tubby protein homolog 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7275
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P50607
Gene Symbols: TUB
Immunogen: KLH conjugated synthetic peptide derived from human TUB 1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TUB 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TUB
Gene Alias:
CELE_F10B5.4; F10B5.4; Rd5; RDOB; retinal degeneration 5; Tub; tub-1; tubby bipartite transcription factor; tubby candidate gene; tubby homolog; tubby homolog (mouse); tubby homologue; Tubby protein; Tubby protein homolog; Tubby protein homolog 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7275
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P50607
Gene Symbols:
TUB
Immunogen:
KLH conjugated synthetic peptide derived from human TUB 1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG