50-198-4854

IL-21 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-4854-Each-of-1 In Stock ₹ 36,897.75

50-198-4854 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

IL-21

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL21

Gene Alias

BOS_16376; CVID11; CX2; IL21; IL-21; ILN; Interleukin; interleukin 21; interleukin 21-like; Interleukin21; Interleukin-21; interleukin-21 isoform; LOC100344172; Za11

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

59067

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q9HBE4

Gene Symbols

IL21

Immunogen

KLH conjugated synthetic peptide derived from human IL-21.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • IL-21 is a 17 kDa immunomodulatory cytokine produced mainly by Natural Killer Cells (NKT), T helper (Th) 17 and T follicular helper (TFH) cells
  • In TFH cells, IL-21 expression leads to autocrine signaling through the IL-21 receptor (IL-21R) and STAT3, which leads to additional transcriptional activation by Bcl6
  • As with IFN gamma for Th1 and IL-4 for Th2 cells, IL-21 is critical for TFH cell development and effector function
  • IL-21 plays a role in T cell-dependent B cell differentiation into plasma cells and memory cells, stimulation of IgG production and induction of apoptotic signaling in naive B cells
  • In Th17 cells, IL-21 expression and autocrine feedback through STAT3, IRF4 and ROR gamma t lead to upregulation of the IL-23R, thereby preparing Th17 cells for maturation and maintenance by the inflammatory cytokine IL-23
  • While upregulating IRF4 and ROR gamma t, IL-21 also mediates the downregulation of Foxp3
  • IL-21 deficient mice are protected from developing colitis upon chemical treatment by their inability to upregulate Th17-associated molecules
  • In comparison, elevated levels of IL-21 are present in chemically-induced colitis mouse models.

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Bioss

50-198-4854

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Antigen:
IL-21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL21

Gene Alias:
BOS_16376; CVID11; CX2; IL21; IL-21; ILN; Interleukin; interleukin 21; interleukin 21-like; Interleukin21; Interleukin-21; interleukin-21 isoform; LOC100344172; Za11

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
59067

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9HBE4

Gene Symbols:
IL21

Immunogen:
KLH conjugated synthetic peptide derived from human IL-21.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4855

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Antigen:
IL-21R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il21r

Gene Alias:
CD360; IL-21 receptor; IL21R; IL-21R; interleukin 21 receptor; Interleukin-21 receptor; LR-beta; Lymphocyte receptor beta; MGC10967; Nilr; Novel cytokine receptor 8; Novel interleukin receptor; NR8; UNQ3121/PRO10273

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
50615

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9HBE5

Gene Symbols:
Il21r

Immunogen:
KLH conjugated synthetic peptide derived from human IL-21R.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4856

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Antigen:
IL-22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL22

Gene Alias:
Cytokine Zcyto18; EGK_03903; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; Iltif; IL-TIF; ILTIF alpha; IL-TIF alpha; Iltifa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; Interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
50616

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9GZX6

Gene Symbols:
IL22

Immunogen:
KLH conjugated synthetic peptide derived from human IL-22.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4857

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Antigen:
IL22RA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il22ra1

Gene Alias:
9130219A07Rik; CRF2-9; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; ENSMUSG00000073746; IL-22 receptor subunit alpha-1; IL22R; IL-22R; IL22R1; IL22RA1; IL-22RA1; IL-22R-alpha-1; ILN; Interleukin; interleukin 22 receptor subunit alpha 1; interleukin 22 receptor, alpha 1; interleukin-22 receptor alpha chain; Interleukin-22 receptor subunit alpha-1; RGD1559655; ZcytoR11

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
58985

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8N6P7

Gene Symbols:
Il22ra1

Immunogen:
KLH conjugated synthetic peptide derived from human IL-22R.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG