Home Products Antibodies Primary Antibodies 50 198 4856
50-198-4856

IL-22 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-4856-Each-of-1 In Stock ₹ 36,897.75

50-198-4856 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

IL-22

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL22

Gene Alias

Cytokine Zcyto18; EGK_03903; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; Iltif; IL-TIF; ILTIF alpha; IL-TIF alpha; Iltifa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; Interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

50616

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q9GZX6

Gene Symbols

IL22

Immunogen

KLH conjugated synthetic peptide derived from human IL-22.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • IL-22 also known as IL-10-related T-cell derived inducible factor, is an alpha helical cytokine and is considered a member of the IFN-IL-10 family, which includes IL-19, IL-20, IL-24, IL-26, IL-28, IL-29, and the type I and II interferons
  • IL-22 is produced mainly by activated T cells and NK cells
  • In humans, the IL-22 gene is located on the q arm of chromosome 12, and is structurally related to IL10
  • IL-22 acts by engaging the heterodimeric receptor complex consisting of primary receptor IL-22R1 and accessory receptor IL-10R2
  • IL-22R1 also binds IL-20 and IL-24; IL-10R2 also binds IL-10, IL-27, IL-28, and IL-29
  • Binding of IL-22 to its receptor complex induces signal transduction, particularly via the JAK-STAT pathway
  • In addition to the membrane-bound IL-22R1/IL-10R2 complex, a soluble single-chain IL-22 receptor termed IL-22BP has been found to antagonize IL-22 binding and signaling
  • IL-22 appears not to directly influence immune cells, and major targets of the cytokine appear to be nonimmune cells, such as cells of the skin, digestive and respiratory system, as well as hepatocytes, and keratinocytes
  • IL-22 has been described as an effector cytokine of the Th17 lineage
  • Along with IL-17A and IL-17F, IL-22 regulates genes associated with innate immunity of the skin
  • IL-17A, IL-17F and IL-22 are all co-expressed by Th17 cells, however, they are differentially regulated
  • The effects of IL-22 include induction of acute phase reactants and antimicrobial proteins, as well as increasing the mobility of keratinocytes
  • IL-22 is highly expressed during chronic inflammation, and found to activate intracellular kinases and transcription factors
  • IL-22 is critical for host defense against infections of extracellular pathogens, and promotes wound-healing responses
  • IL-22 is upregulated in activated T cells
  • IL-22 has been reported to mediate IL-23-induced acanthosis and dermal inflammation through activation of STAT3.

Compare Similar Items

Show Difference

Img

Bioss

50-198-4856

--

Antigen:
IL-22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL22
Gene Alias:
Cytokine Zcyto18; EGK_03903; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; Iltif; IL-TIF; ILTIF alpha; IL-TIF alpha; Iltifa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; Interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
50616
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q9GZX6
Gene Symbols:
IL22
Immunogen:
KLH conjugated synthetic peptide derived from human IL-22.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bioss

50-198-4857

--

Antigen:
IL22RA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Il22ra1
Gene Alias:
9130219A07Rik; CRF2-9; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; ENSMUSG00000073746; IL-22 receptor subunit alpha-1; IL22R; IL-22R; IL22R1; IL22RA1; IL-22RA1; IL-22R-alpha-1; ILN; Interleukin; interleukin 22 receptor subunit alpha 1; interleukin 22 receptor, alpha 1; interleukin-22 receptor alpha chain; Interleukin-22 receptor subunit alpha-1; RGD1559655; ZcytoR11
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
58985
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q8N6P7
Gene Symbols:
Il22ra1
Immunogen:
KLH conjugated synthetic peptide derived from human IL-22R.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bioss

50-198-4859

--

Antigen:
IL-31RA/CRL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL31RA
Gene Alias:
class I cytokine receptor; CRL; CRL 3; CRL3; CRL3Glmr; cytokine receptor NR10; Cytokine receptor-like 3; GLM R; Glmr; GLM-R; GLM-RMGC125346; GP130 like receptor; Gp130-like monocyte receptor; Gp130-like receptor; GPL; HGLM R; HGLMR; hGLM-R; IL 31RA; IL-31 receptor subunit alpha; IL31R subunit alpha; IL-31R subunit alpha; Il31ra; IL-31RA; IL-31RAGPLCRL; IL-31R-alpha; interleukin 31 receptor A; interleukin 31RA; Interleukin-31 receptor subunit alpha; MGC125346; mGLM-R; Novel cytokine receptor 10; NR10; PLCA 2; PLCA2; PRO21384; soluble type I cytokine receptor CRL3; UNQ6368/PRO21073/PRO21384; ZcytoR17
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
133396
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q8NI17
Gene Symbols:
IL31RA
Immunogen:
KLH conjugated synthetic peptide derived from human IL-31RA .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bioss

50-198-4861

--

Antigen:
IL-33
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL33
Gene Alias:
9230117N10Rik; C9orf26; DVS27; DVS27-related protein; H-IL-33; IL1F11; IL-1F11; IL33; IL-33; ILN; Interleukin; interleukin 33; Interleukin-1 family member 11; Interleukin33; Interleukin-33; Interleukin-33 (109-270); Interleukin-33 (95-270); Interleukin-33 (99-270); Interleukin-33(102-266); Interleukin-33(109-266); NFEHEV; NFHEV; NF-HEV; nuclear factor for high endothelial venules; Nuclear factor from high endothelial venules; RGD1311155; RP11-575C20.2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
90865
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
O95760
Gene Symbols:
IL33
Immunogen:
KLH conjugated synthetic peptide derived from mouse IL-33.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG