50-198-5106

Phospho-beta Arrestin 1Ser412 (Ser412) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5106-Each-of-1 In Stock ₹ 36,897.75

50-198-5106 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-beta Arrestin 1Ser412 (Ser412)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARRB1

Gene Alias

1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; Arrestin beta-1; arrestin, beta 1; Arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; Beta-arrestin-1; BOS_14994; G430100A01Rik; Non-visual arrestin-2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

408

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P49407

Gene Symbols

ARRB1

Immunogen

KLH conjugated synthetic phosphopeptide derived from human beta-Arrestin 1 around the phosphorylation site of Ser412.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system
  • Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor)
  • After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G-protein receptor kinases (GRKs) on serine residues
  • Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane
  • Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.

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Img

Bioss

50-198-5106

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Antigen:
Phospho-beta Arrestin 1Ser412 (Ser412)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARRB1

Gene Alias:
1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; Arrestin beta-1; arrestin, beta 1; Arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; Beta-arrestin-1; BOS_14994; G430100A01Rik; Non-visual arrestin-2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
408

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P49407

Gene Symbols:
ARRB1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human beta-Arrestin 1 around the phosphorylation site of Ser412.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5107

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Antigen:
Phospho-Aurora B (Thr198)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AURKB

Gene Alias:
AIE2; AIK1; Aik2; AIK3; AIM1; AIM-1; AIRK2; AIRK3; AL022959; Ark2; ARK-2; ARK3; ARK-3; AurB; Aurkb; aurkb-sv1; aurkb-sv2; AURKC; Aurora 1; Aurora 3; Aurora- and IPL1-like midbody-associated protein 1; aurora B; Aurora kinase B; aurora kinase B; serine/threonine-protein kinase 12; aurora kinase B-Sv1; aurora kinase B-Sv2; Aurora kinase C; Aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; BOS_18918; EC 2.7.11.1; IPL1; NP_004208; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B; STK1; STK-1; STK12; STK13; STK5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9212

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q96GD4

Gene Symbols:
AURKB

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Aurora B around the phosphorylation site of Thr232.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5110

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Antigen:
Phospho-Bcl-2 (Ser70)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5112

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Antigen:
Phospho-Btk (Ser180)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BTK

Gene Alias:
agammaglobulinaemia tyrosine kinase; Agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton′s tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; Kinase EMB; MGC126261; MGC126262; OTTHUMP00000023677; PSCTK1; RP1-164F3.2; truncated Bruton agammaglobulinemia tyrosine kinase; Tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); xid; XLA; X-linked immune deficiency

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
695

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q06187

Gene Symbols:
BTK

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Btk around the phosphorylation site of Ser180 [GS (p-S)HR].

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG