50-198-5394

Phospho-STAT3 (Ser727) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5394-Each-of-1 In Stock ₹ 36,897.75

50-198-5394 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-STAT3 (Ser727)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STAT3

Gene Alias

1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6774

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P40763

Gene Symbols

STAT3

Immunogen

KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Ser727.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
  • Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
  • STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
  • Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
  • In humans, the STAT3 gene is located on the q arm of chromosome 17
  • STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
  • The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
  • STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
  • The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
  • Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
  • Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.

Compare Similar Items

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Img

Bioss

50-198-5394

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Antigen:
Phospho-STAT3 (Ser727)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT3

Gene Alias:
1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6774

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P40763

Gene Symbols:
STAT3

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Ser727.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5395

--


Antigen:
Phospho-Stat4 (Tyr693)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT4

Gene Alias:
CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; STAT4; STATI4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6775

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q14765

Gene Symbols:
STAT4

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Stat4 around the phosphorylation site of Tyr693.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5396

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Antigen:
Phospho-Syk (Tyr525, Tyr526)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Syk

Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; Spleen tyrosine kinase; Syk; Sykb; Tyrosine-protein kinase SYK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20963, 25155, 6850

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P43405, P48025, Q64725

Gene Symbols:
Syk

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyr525/526.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5398

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Antigen:
Phospho-TAK1 (Thr184)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K7

Gene Alias:
B430101B05; BOS_9732; C87327; hypothetical protein LOC553788; I79_000697; M3K7; Map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; Mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; TAK1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; Transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6885

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O43318

Gene Symbols:
MAP3K7

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human TAK1 around the phosphorylation site of Thr184.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG