50-198-5621

Phospho-HSF1 (Ser326) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5621-Each-of-1 In Stock ₹ 36,897.75

50-198-5621 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-HSF1 (Ser326)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Hsf1

Gene Alias

AA960185; BOS_13649; heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3297

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q00613

Gene Symbols

Hsf1

Immunogen

KLH conjugated synthetic phosphopeptide derived from human HSF1 around the phosphorylation site of Ser326.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • All organisms respond to elevated temperatures and a variety of environmental stresses by rapid synthesis of heat shock RNAs and proteins
  • The regulation of heat shock gene transcription is mediated by the transcriptional activator, heat shock factor (HSF), which binds to heat shock response elements (HSEs)
  • These HSEs are found as three repeats of a 5-nucleotide {nGAAn} module, arranged in alternating orientation and present upstream of all heat shock genes
  • The HSEs are highly conserved among species yet HSF purified from yeast, Drosophila and human have different molecular weights and the proteins do not show significant immunological cross reaction
  • Two HSFs have been identified in human cells, HSF1 and HSF2, which bind to the same HSEs and have 38% sequence identity
  • These factors are activated by distinct stimuli, HSF1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF2 is activated during hemin-mediated differentiation of human erythroleukemia cells
  • HSF1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity
  • Through an unknown signal generated during stress, HSF1 becomes activated to a nuclear localized, trimeric state which binds to DNA
  • The phosphorylation of HSF1 is necessary for maximal transcription of heat shock genes.

Compare Similar Items

Show Difference

Img

Bioss

50-198-5621

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Antigen:
Phospho-HSF1 (Ser326)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hsf1

Gene Alias:
AA960185; BOS_13649; heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3297

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q00613

Gene Symbols:
Hsf1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human HSF1 around the phosphorylation site of Ser326.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5622

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Antigen:
Phospho-CK8 (Ser24)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT8

Gene Alias:
AA960620; AL022697; AU019895; BOS_5041; C CY K2C8; CARD2; cb186; CK 8; CK8; CK-8; CYK8; CYKER; cytokeratin 8; Cytokeratin endo A; Cytokeratin-8; Cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; K2C8; K8; K-8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; Keratin-8; KO; Krt-2.8; krt2-8; Krt8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; Type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3856

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P05787

Gene Symbols:
KRT8

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CK8 around the phosphorylation site of Ser24.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5623

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Antigen:
Phospho-Paxillin (Tyr31)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PXN

Gene Alias:
adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; PXN; pxna; testicular tissue protein Li 134; wu:fw71f12

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5829

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P49023

Gene Symbols:
PXN

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Paxillin around the phosphorylation site of Tyr31.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5626

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Antigen:
ARA24

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAN

Gene Alias:
AAF30287; Androgen receptor-associated protein 24; ARA24; ARA25; CG1404; CG1404 gene product from transcript CG1404-RC; CG1404-PA; CG1404-PB; CG1404-PC; CG1404-PD; Dmel\CG1404; Dmel_CG1404; dran; Gsp1; GTPase Ran; GTP-binding nuclear protein Ran; guanosine triphosphatase Ran; I79_024397; l(1)G0075; member RAS oncogene family; OK/SW-cl.81; OTTHUMP00000166078; OTTHUMP00000166102; Q9VZ23; ran; Ran GTPase; ran GTP-binding protein; RAN, member RAS oncogene family; RAN, member RAS oncogene family L homeolog; ran.L; ran-1; Ran10A; RanGTP; RanGTPase; Ran-PA; Ran-PB; Ran-PC; Ran-PD; RanTC4; Rasl2-8; Ras-like protein TC4; Ras-related nuclear protein; TC4; XELAEV_18007741mg; xran

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5901

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P62826

Gene Symbols:
RAN

Immunogen:
KLH conjugated synthetic peptide derived from human ARA24.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG