50-198-6754

BubR1 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-6754-Each-of-1 In Stock ₹ 36,897.75

50-198-6754 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

BubR1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BUB1B

Gene Alias

AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; BUB1B; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

701

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O60566

Gene Symbols

BUB1B

Immunogen

KLH conjugated synthetic peptide derived from human BubR1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • BUBR1 is a member of the Ser/Thr protein kinase family
  • It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle
  • Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to malignant transformations
  • Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
  • They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
  • hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
  • BUBR1 has been detected in human cancers
  • It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.

Compare Similar Items

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Img

Bioss

50-198-6754

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Antigen:
BubR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BUB1B

Gene Alias:
AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; BUB1B; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
701

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O60566

Gene Symbols:
BUB1B

Immunogen:
KLH conjugated synthetic peptide derived from human BubR1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6755

--


Antigen:
HEC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NDC80

Gene Alias:
2610020P18Rik; AV139730; HEC; HEC1; HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; Kinetochore protein Hec1; Kinetochore protein NDC80 homolog; Kinetochore-associated protein 2; KNTC2; Ndc80; NDC80 homolog, kinetochore complex component; NDC80 homolog, kinetochore complex component (S. cerevisiae); NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component; putative kinetochore protein NDC80 like protein; Retinoblastoma-associated protein HEC; TID3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10403

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O14777

Gene Symbols:
NDC80

Immunogen:
KLH conjugated synthetic peptide derived from human HEC1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6759

--


Antigen:
PCGF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCGF1

Gene Alias:
2010002K04Rik; AU024121; nervous system polycomb 1; Nervous system Polycomb-1; NSPC1; Pcgf1; polycomb group ring finger 1; Polycomb group RING finger protein 1; RING finger protein 68; RNF3A-2; RNF68

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
84759

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9BSM1

Gene Symbols:
PCGF1

Immunogen:
KLH conjugated synthetic peptide derived from human PCGF1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6761

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Antigen:
TACC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TACC2

Gene Alias:
anti zuai-1; Anti-Zuai-1; AZU-1; ECTACC; mKIAA4180; MNCb-3527; RP11-296H2.1; Tacc2; transforming acidic coiled coil 2; transforming acidic coiled-coil containing protein 2; transforming acidic coiled-coil containing protein 2 variant 3; Transforming acidic coiled-coil-containing protein 2; transforming, acidic coiled-coil containing protein 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10579

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O95359

Gene Symbols:
TACC2

Immunogen:
KLH conjugated synthetic peptide derived from human TACC2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG