50-198-7893

HCA57 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-7893-Each-of-1 In Stock ₹ 36,897.75

50-198-7893 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

HCA57

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DNAJA3

Gene Alias

1200003J13Rik; 1810053A11Rik; C81173; DnaJ (Hsp40) homolog, subfamily A, member 3; DnaJ heat shock protein family (Hsp40) member A3; DnaJ homolog subfamily A member 3, mitochondrial; DnaJ protein Tid-1; Dnaja3; HCA57; Hepatocellular carcinoma-associated antigen 57; hTid-1; mTid-1; TID1; Tid-1; Tid1l; Tumorous imaginal discs protein Tid56 homolog

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

9093

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q96EY1

Gene Symbols

DNAJA3

Immunogen

KLH conjugated synthetic peptide derived from human TID1/HCA57.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • TID1 is a human homolog of the Drosophila tumor suppressor lethal (2) tumorous imaginal discs, l(2)tid and encodes two mitochondrial matrix localized splice variants of human Tid-1 designated hTid-1S and hTid-1L
  • These proteins are the conserved members of the DnaJ family of proteins which act as cochaperones for mitochondrial Hsp70
  • They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity
  • Expression of hTid-1L increases apoptosis induced by DNA damaging agents as mitomycin-C and TNF-a
  • A J-domain mutant of hTid-1L can dominantly suppress apoptosis and in sharp contrast the J-domain mutant of hTid-1S increases apoptosis
  • Expression of hTid-1S and hTid-1L affects cytochrome c release from the mitochondria and caspase 3 activation, while activation of caspase 8 is unaffected
  • It is strongly suggested that these two splice variants exert their anti- and pro- apoptotic effects through discrete substrates and activities
  • Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals.

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Img

Bioss

50-198-7893

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Antigen:
HCA57

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNAJA3

Gene Alias:
1200003J13Rik; 1810053A11Rik; C81173; DnaJ (Hsp40) homolog, subfamily A, member 3; DnaJ heat shock protein family (Hsp40) member A3; DnaJ homolog subfamily A member 3, mitochondrial; DnaJ protein Tid-1; Dnaja3; HCA57; Hepatocellular carcinoma-associated antigen 57; hTid-1; mTid-1; TID1; Tid-1; Tid1l; Tumorous imaginal discs protein Tid56 homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9093

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q96EY1

Gene Symbols:
DNAJA3

Immunogen:
KLH conjugated synthetic peptide derived from human TID1/HCA57.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7894

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Antigen:
FIS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FIS1

Gene Alias:
2010003O14Rik; CGI-135; Fis1; fis1 {ECO:0000250; FIS1 homolog; fission 1 (mitochondrial outer membrane) homolog; fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); fission 1 (mitochondrial outer membrane) homolog (yeast); fission, mitochondrial 1; H_NH0132A01.6; hFis1; Mitochondrial fission 1 protein; mitochondrial fission molecule; rFis1; tetratricopeptide repeat domain 11; Tetratricopeptide repeat protein 11; TPR repeat protein 11; Ttc11; UniProtKB:Q9Y3D6}

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51024

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9Y3D6

Gene Symbols:
FIS1

Immunogen:
KLH conjugated synthetic peptide derived from human FIS1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7896

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Antigen:
DFFB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DFFB

Gene Alias:
2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; Caspase-activated deoxyribonuclease; caspase-activated DNase; Caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; Dffb; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1677

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O76075

Gene Symbols:
DFFB

Immunogen:
KLH conjugated synthetic peptide derived from human DFFB.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7898

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Antigen:
DNase 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNASE1

Gene Alias:
AI788650; Deoxyribonuclease 1; Deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; DNASE1; DNaseI; DNL 1; Dnl1; Dornase alfa; DRNI; FLJ38093; human urine deoxyribonuclease I

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1773

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P24855

Gene Symbols:
DNASE1

Immunogen:
KLH conjugated synthetic peptide derived from human DNase I.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG