50-198-9520

Alas1 Rabbit anti-Human, Clone: 1G11, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-9520-Each-of-1 In Stock ₹ 47,374.57

50-198-9520 - Each of 1

₹ 47,374.57

In Stock

Quantity

1

Base Price: ₹ 47,374.57

GST (18%): ₹ 8,527.423

Total Price: ₹ 55,901.993

Antigen

Alas1

Classification

Monoclonal

Concentration

1 μg/mL

Formulation

TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.

P13196

Gene Symbols

ALAS1

Immunogen

Recombinant human Alas1 protein, around C-terminal 200aa.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunofluorescence, Western Blot

Clone

1G11

Conjugate

Unconjugated

Gene

ALAS1

Gene Alias

5′-aminolevulinate synthase 1; 5-aminolevulinate synthase 1; 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALA-S; Alas1; Alas-1; ALAS3; ALASH; ALAS-H; ALAS-N; aminolevulinate synthase H; aminolevulinate, delta-, synthase 1; aminolevulinic acid synthase 1; Delta-ALA synthase 1; delta-ALA synthetase; Delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; OK/SW-cl.121; succinyl-CoA: glycine C-succinyl transferase

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

211

Content And Storage

-20°C

Form

Liquid

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Description

  • ALAS-1 is a nuclear-encoded mitochondrial matrix enzyme which catalyzes the condensation of glycine with succinyl-CoA to form delta-amino levulinate, CO2 and CoA
  • It regulates the first and rate-limiting step of heme biosynthetic pathway
  • It is one of the two isoforms of ALAS and is a pyridoxal-5′ phosphate dependant housekeeping enzyme
  • It is ubiquitously expressed and is responsible of providing heme for cytochromes and other hemoproteins
  • ALAS1 in liver undergoes negative feedback regulation by heme
  • Transcription of ALAS1 gene is stimulated by cAMP and respiratory uncoupling whereas Phorbol esters and insulin repress ALAS1 gene expression
  • ALAS1 is suggested to be involved in reciprocal regulation of Heme biosynthesis and circadian clock suggesting a potential target for treatment of circadian disorders
  • ALAS1 gene expression is down regulated in Acute Liver failure resulting in altered heme metabolism and liver function.

Compare Similar Items

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Bioss

50-198-9520

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Antigen:
Alas1

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P13196

Gene Symbols:
ALAS1

Immunogen:
Recombinant human Alas1 protein, around C-terminal 200aa.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Western Blot

Clone:
1G11

Conjugate:
Unconjugated

Gene:
ALAS1

Gene Alias:
5′-aminolevulinate synthase 1; 5-aminolevulinate synthase 1; 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALA-S; Alas1; Alas-1; ALAS3; ALASH; ALAS-H; ALAS-N; aminolevulinate synthase H; aminolevulinate, delta-, synthase 1; aminolevulinic acid synthase 1; Delta-ALA synthase 1; delta-ALA synthetase; Delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; OK/SW-cl.121; succinyl-CoA: glycine C-succinyl transferase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
211

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9521

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Antigen:
A-RAF

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P10398

Gene Symbols:
ARAF

Immunogen:
Recombinant human A-RAF protein, around 150-300aa.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
24D1

Conjugate:
Unconjugated

Gene:
ARAF

Gene Alias:
1200013E08Rik; ARAF; A-raf; A-Raf proto-oncogene serine/threonine-protein kinase; A-Raf proto-oncogene, serine/threonine kinase; Araf1; A-raf-1; AW495444; Oncogene ARAF1; PKS; PKS2; Proto-oncogene A-Raf; Proto-oncogene A-Raf-1; Proto-oncogene Pks; Raf related protein; RAFA1; raf-related oncogene; Ras-binding protein; Ras-binding protein DA-Raf; RP1-230G1.1; Serine/threonine-protein kinase A-Raf; v-raf murine sarcoma 3611 viral oncogene homolog; v-raf murine sarcoma 3611 viral oncogene homolog 1; v-raf murine sarcoma 3611 viral oncogene-like protein; v-raf oncogene homolog 1 (murine sarcoma 3611 virus)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
369

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9524

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Antigen:
Aurora B

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
Q96GD4

Gene Symbols:
AURKB

Immunogen:
Recombinant human Aurora B protein, around N-terminal 150aa.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
1G9

Conjugate:
Unconjugated

Gene:
AURKB

Gene Alias:
AIE2; AIK1; Aik2; AIK3; AIM1; AIM-1; AIRK2; AIRK3; AL022959; Ark2; ARK-2; ARK3; ARK-3; AurB; Aurkb; aurkb-sv1; aurkb-sv2; AURKC; Aurora 1; Aurora 3; Aurora- and IPL1-like midbody-associated protein 1; aurora B; Aurora kinase B; aurora kinase B; serine/threonine-protein kinase 12; aurora kinase B-Sv1; aurora kinase B-Sv2; Aurora kinase C; Aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; BOS_18918; EC 2.7.11.1; IPL1; NP_004208; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B; STK1; STK-1; STK12; STK13; STK5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9212

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9527

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Antigen:
BCL-2

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
Recombinant human BCL-2 protein, around 50-150aa.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2C4

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20°C

Form:
Liquid