50-198-9527
BCL-2 Mouse anti-Human, Clone: 2C4, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-9527-Each-of-1 | In Stock | ₹ 45,440.92 |
50-198-9527 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,440.92
GST (18%): ₹ 8,179.366
Total Price: ₹ 53,620.286
Antigen
BCL-2
Classification
Monoclonal
Concentration
1 μg/mL
Formulation
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.
P10415
Gene Symbols
Bcl2
Immunogen
Recombinant human BCL-2 protein, around 50-150aa.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
2C4
Conjugate
Unconjugated
Gene
Bcl2
Gene Alias
Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
596
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
Compare Similar Items
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Antigen: BCL-2
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P10415
Gene Symbols: Bcl2
Immunogen: Recombinant human BCL-2 protein, around 50-150aa.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 2C4
Conjugate: Unconjugated
Gene: Bcl2
Gene Alias: Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 596
Content And Storage: -20°C
Form: Liquid
Antigen:
BCL-2
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P10415
Gene Symbols:
Bcl2
Immunogen:
Recombinant human BCL-2 protein, around 50-150aa.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
2C4
Conjugate:
Unconjugated
Gene:
Bcl2
Gene Alias:
Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
596
Content And Storage:
-20°C
Form:
Liquid
Antigen: BCL2A1
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: Q16548
Gene Symbols: BCL2A1
Immunogen: Recombinant human BCL2A1 protein, full length.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 3E4
Conjugate: Unconjugated
Gene: BCL2A1
Gene Alias: A1; A1-A; ACC1; ACC-1; ACC2; ACC-2; B cell leukemia/lymphoma 2 related protein A1a; BB218357; B-cell leukemia/lymphoma 2 related protein A1; B-cell leukemia/lymphoma 2 related protein A1a; B-cell leukemia/lymphoma 2 related protein A1d; BCL2 related protein A1; BCL2A1; Bcl2a1a; Bcl2a1d; BCL2L5; Bcl2-L-5; Bcl-2-like protein 5; Bcl-2-related protein A1; BCL2-related protein A1; BCL2-related protein A1d; BFL1; Bfl-1; GRS; GRS protein; HBPA1; hematopoietic BCL2-related protein A1; Hemopoietic-specific early response protein; Protein BFL-1; Protein GRS
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 597
Content And Storage: -20°C
Form: Liquid
Antigen:
BCL2A1
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
Q16548
Gene Symbols:
BCL2A1
Immunogen:
Recombinant human BCL2A1 protein, full length.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
3E4
Conjugate:
Unconjugated
Gene:
BCL2A1
Gene Alias:
A1; A1-A; ACC1; ACC-1; ACC2; ACC-2; B cell leukemia/lymphoma 2 related protein A1a; BB218357; B-cell leukemia/lymphoma 2 related protein A1; B-cell leukemia/lymphoma 2 related protein A1a; B-cell leukemia/lymphoma 2 related protein A1d; BCL2 related protein A1; BCL2A1; Bcl2a1a; Bcl2a1d; BCL2L5; Bcl2-L-5; Bcl-2-like protein 5; Bcl-2-related protein A1; BCL2-related protein A1; BCL2-related protein A1d; BFL1; Bfl-1; GRS; GRS protein; HBPA1; hematopoietic BCL2-related protein A1; Hemopoietic-specific early response protein; Protein BFL-1; Protein GRS
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
597
Content And Storage:
-20°C
Form:
Liquid
Antigen: Bcl-XL
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: Q07817
Gene Symbols: BCL2L1
Immunogen: Recombinant human Bcl-XL protein, around 1-100aa.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 12C5
Conjugate: Unconjugated
Gene: BCL2L1
Gene Alias: anti-apoptosis regulatory protein; Apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; Bcl2l1; Bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-X; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 598
Content And Storage: -20°C
Form: Liquid
Antigen:
Bcl-XL
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
Q07817
Gene Symbols:
BCL2L1
Immunogen:
Recombinant human Bcl-XL protein, around 1-100aa.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
12C5
Conjugate:
Unconjugated
Gene:
BCL2L1
Gene Alias:
anti-apoptosis regulatory protein; Apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; Bcl2l1; Bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-X; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
598
Content And Storage:
-20°C
Form:
Liquid
Antigen: Cdk4
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P11802
Gene Symbols: Cdk4
Immunogen: Recombinant human Cdk4 protein, around C-terminal 101aa.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2c
Applications: Western Blot
Clone: 2F6
Conjugate: Unconjugated
Gene: Cdk4
Gene Alias: BOS_5594; CDK4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; Cyclin-dependent kinase 4; MGC14458; p34/cdk4; PSK-J3; serine/threonine kinase
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1019
Content And Storage: -20°C
Form: Liquid
Antigen:
Cdk4
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P11802
Gene Symbols:
Cdk4
Immunogen:
Recombinant human Cdk4 protein, around C-terminal 101aa.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2c
Applications:
Western Blot
Clone:
2F6
Conjugate:
Unconjugated
Gene:
Cdk4
Gene Alias:
BOS_5594; CDK4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; Cyclin-dependent kinase 4; MGC14458; p34/cdk4; PSK-J3; serine/threonine kinase
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1019
Content And Storage:
-20°C
Form:
Liquid