50-198-9943

Bcl2 Mouse anti-Human, Clone: 8B5, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-9943-Each-of-1 In Stock ₹ 45,440.92

50-198-9943 - Each of 1

₹ 45,440.92

In Stock

Quantity

1

Base Price: ₹ 45,440.92

GST (18%): ₹ 8,179.366

Total Price: ₹ 53,620.286

Antigen

Bcl2

Classification

Monoclonal

Concentration

1 μg/mL

Formulation

TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.

P10415

Gene Symbols

Bcl2

Immunogen

KLH conjugated synthetic peptide derived from human Bcl2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

8B5

Conjugate

Unconjugated

Gene

Bcl2

Gene Alias

Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

596

Content And Storage

-20°C

Form

Liquid

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Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

Show Difference

Img

Bioss

50-198-9943

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Antigen:
Bcl2

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
KLH conjugated synthetic peptide derived from human Bcl2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
8B5

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9945

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Antigen:
CK7

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.:
P08729

Gene Symbols:
KRT7

Immunogen:
KLH conjugated synthetic peptide derived from human CK7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
1000

Conjugate:
Unconjugated

Gene:
KRT7

Gene Alias:
C SCL; CK7; CK-7; Cytokeratin 7; Cytokeratin-7; D15Wsu77e; K2C7; K7; Kb7; keratin 7; keratin 7, type II; keratin associated protein 7.1; keratin complex 2, basic, gene 7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; keratin-associated protein 7-1; keratin-associated protein 7-1-like protein; Krt2-7; KRT7; krt7 {ECO:0000250; LOC100755511; LOC100861181; MGC129731; MGC3625; Sarcolectin; SCL; type II keratin Kb7; type II mesothelial keratin K7; Type-II keratin Kb7; UniProtKB:P08729}

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3855

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9946

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Antigen:
GFAP

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.:
P14136

Gene Symbols:
GFAP

Immunogen:
Recombinant mouse GFAP full length.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
7D8

Conjugate:
Unconjugated

Gene:
GFAP

Gene Alias:
AI836096; ALXDRD; BOS_19250; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GFAP; GFAP epsilon; gfap protein; gfapl; Glial fibrillary acidic protein; glial fibrillary acidic protein alpha; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2670

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9948

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Antigen:
Methyl-Histone H3 (Lys79)

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.:
Q16695

Gene Symbols:
H3-4

Immunogen:
KLH conjugated synthetic peptide derived from human Histone H3 (tri methyl K79).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
3C7

Conjugate:
Unconjugated

Gene:
H3-4

Gene Alias:
H3 histone family, member T; H3.4; H3/g; H3/t; H3FT; H3t; HIST3H3; histone 3, H3; histone cluster 3, H3; Histone H3.1t

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8290

Content And Storage:
-20°C

Form:
Liquid