50-198-9604

Phospho-c-Myc (Ser62) Rabbit anti-Human, Clone: 1A7, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-9604-Each-of-1 In Stock ₹ 47,374.57

50-198-9604 - Each of 1

₹ 47,374.57

In Stock

Quantity

1

Base Price: ₹ 47,374.57

GST (18%): ₹ 8,527.423

Total Price: ₹ 55,901.993

Antigen

Phospho-c-Myc (Ser62)

Classification

Monoclonal

Concentration

1 μg/mL

Formulation

TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.

P01106

Gene Symbols

MYC

Immunogen

Synthetic peptide derived from human c-Myc (S62), around 50-100aa (phospho S62).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

1A7

Conjugate

Unconjugated

Gene

MYC

Gene Alias

AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4609

Content And Storage

-20°C

Form

Liquid

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Description

  • The c-Myc protein is a 62 kDa transcription factor that is encoded by the c-Myc gene on human chromosome 8q24
  • c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression
  • The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation
  • Studies have shown that c-Myc is essential for vasculogenesis and angiogenesis in tumor development, which distributes blood throughout the cells
  • The c-myc oncogene (p62 c-myc) is involved in the control of normal cellular proliferation and differentiation, and the deregulated expression of c-Myc induces apoptosis in different cell types
  • Antibodies against c-myc epitopes recognize overexpressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins
  • c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease
  • Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas
  • Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (delta light chain); or 22 (light chain) is described in Burkitts lymphoma and other B-cell lymphoproliferative conditions
  • An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.

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Show Difference

Img

Bioss

50-198-9604

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Antigen:
Phospho-c-Myc (Ser62)

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P01106

Gene Symbols:
MYC

Immunogen:
Synthetic peptide derived from human c-Myc (S62), around 50-100aa (phospho S62).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
1A7

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4609

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9613

--


Antigen:
Phospho-Glycogen synthase 1 (Ser641)

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P13807

Gene Symbols:
Gys1

Immunogen:
Synthetic peptide derived from human Glycogen synthase 1 (S641), around 630-680aa (phospho S641).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
10C1

Conjugate:
Unconjugated

Gene:
Gys1

Gene Alias:
EC 2.4.1.11; Glycogen [starch] synthase, muscle; glycogen synthase; glycogen synthase 1; glycogen synthase 1 (muscle); glycogen synthase 1, muscle; glycogen synthase 3, brain; GSY; Gys; GYS1; Gys3; MGS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2997

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9619

--


Antigen:
Phospho-IKB alpha (Ser32)

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P25963

Gene Symbols:
NFKBIA

Immunogen:
Synthetic peptide derived from human IKB alpha (Ser32) around 1-50 amino acids.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
13E7

Conjugate:
Unconjugated

Gene:
NFKBIA

Gene Alias:
AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4792

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9625

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Antigen:
Phospho-p53 (Ser376)

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
Synthetic peptide derived from human p53 (S376), around 350-400aa (phospho S376).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
7C9

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
-20°C

Form:
Liquid