50-198-9668

MERTK Rabbit anti-Human, Clone: 1C11, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-9668-Each-of-1 In Stock ₹ 47,374.57

50-198-9668 - Each of 1

₹ 47,374.57

In Stock

Quantity

1

Base Price: ₹ 47,374.57

GST (18%): ₹ 8,527.423

Total Price: ₹ 55,901.993

Antigen

MERTK

Classification

Monoclonal

Concentration

1 μg/mL

Formulation

TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.

Q12866

Gene Symbols

Mertk

Immunogen

Recombinant human MERTK between 1 to 100 amino acids.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Clone

1C11

Conjugate

Unconjugated

Gene

Mertk

Gene Alias

c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; Mertk; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; Receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10461

Content And Storage

-20°C

Form

Liquid

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Description

  • Description Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6
  • Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
  • Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
  • Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
  • MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
  • Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
  • Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Compare Similar Items

Show Difference

Img

Bioss

50-198-9668

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Antigen:
MERTK

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
Q12866

Gene Symbols:
Mertk

Immunogen:
Recombinant human MERTK between 1 to 100 amino acids.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
1C11

Conjugate:
Unconjugated

Gene:
Mertk

Gene Alias:
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; Mertk; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; Receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10461

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9669

--


Antigen:
Caspase 3

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P42574

Gene Symbols:
CASP3

Immunogen:
__

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry, Western Blot

Clone:
5A3

Conjugate:
Unconjugated

Gene:
CASP3

Gene Alias:
A830040C14Rik; AC-3; Apopain; Apopain precursor; CASP3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; Caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; CPP32; CPP-32; CPP32B; CPP32beta; Cysteine protease CPP32; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; Protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
836

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9671

--


Antigen:
BCL2

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
Recombinant human Bcl-2 between 1 to 200 amino acids.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone:
5F7

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-9675

--


Antigen:
VEGF Receptor 1

Classification:
Monoclonal

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH

Gene Accession No.:
P17948

Gene Symbols:
FLT1

Immunogen:
Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Clone:
3A6

Conjugate:
Unconjugated

Gene:
FLT1

Gene Alias:
AI323757; Embryonic receptor kinase 2; Emrk2; FLT; FLT1; FLT-1; fms related tyrosine kinase 1; Fms-like tyrosine kinase 1; FMS-related tyrosine kinase 1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FRT; i21; sFlt1; soluble VEGFR 1; sVEGFR 1; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; Vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor-1; Vascular permeability factor receptor; VEGF R1; Vegfr1; VEGFR-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2321

Content And Storage:
-20°C

Form:
Liquid