50-198-9866

Phospho-MERTK (Tyr749) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-9866-Each-of-1 In Stock ₹ 36,897.75

50-198-9866 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-MERTK (Tyr749)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mertk

Gene Alias

c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; Mertk; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; Receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10461

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 μg/mL

Formulation

TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.

Q12866

Gene Symbols

Mertk

Immunogen

KLH conjugated synthesised phosphopeptide derived from human MERTK around the phosphorylation site of Tyr749.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Description Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6
  • Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
  • Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
  • Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
  • MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
  • Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
  • Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Compare Similar Items

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Img

Bioss

50-198-9866

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Antigen:
Phospho-MERTK (Tyr749)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mertk

Gene Alias:
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; Mertk; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; Receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10461

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.:
Q12866

Gene Symbols:
Mertk

Immunogen:
KLH conjugated synthesised phosphopeptide derived from human MERTK around the phosphorylation site of Tyr749.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-9869

--


Antigen:
MYADM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYADM

Gene Alias:
MYADM; myeloid associated differentiation marker; myeloid upregulated protein; Myeloid up-regulated protein; Myeloid-associated differentiation marker; Protein SB135; SB135; UNQ553/PRO1110

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
91663

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.:
Q96S97

Gene Symbols:
MYADM

Immunogen:
KLH conjugated synthetic peptide derived from human MYADM .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-9872

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Antigen:
NMT55

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nono

Gene Alias:
54 kDa nuclear RNA- and DNA-binding protein; 55 kDa nuclear protein; AA407051; AV149256; DNA-binding p52/p100 complex, 52 kDa subunit; HGNC:7871; LOC100346936; LOC100348685; MRXS34; NMT-1; NMT55; nonA; Nono; NonO protein; non-POU domain containing, octamer-binding; non-POU domain containing, octamer-binding-like; non-POU domain-containing octamer (ATGCAAAT) binding protein; Non-POU domain-containing octamer-binding protein; non-POU-domain-containing; non-POU-domain-containing, octamer binding protein; non-POU-domain-containing, octamer-binding protein; NRB54; P54; p54(nrb); p54nrb; PPP1R114; protein phosphatase 1, regulatory subunit 114; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)-like

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4841

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.:
Q15233

Gene Symbols:
Nono

Immunogen:
KLH conjugated synthetic peptide derived from human NMT55.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-9876

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Antigen:
PSME1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSME1

Gene Alias:
11S regulator complex subunit alpha; 29-kD MCP activator subunit; Activator of multicatalytic protease subunit 1; AW413925; epididymis secretory sperm binding protein Li 129m; HEL-S-129m; I79_008549; IFI5111; IGUP I-5111; Interferon gamma up-regulated I-5111 protein; interferon-gamma IEF SSP 5111; interferon-gamma-inducible protein 5111; MGC8628; OTTHUMP00000164702; PA28 alpha subunit; PA28a; PA28alpha; protease (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) activator subunit 1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); Proteasome activator 28 subunit alpha; Proteasome activator complex subunit 1; proteasome activator subunit 1; PSME1; REGalpha; REG-alpha

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5720

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 μg/mL

Formulation:
TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH

Gene Accession No.:
Q06323

Gene Symbols:
PSME1

Immunogen:
KLH conjugated synthetic peptide derived from human PSME1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG