50-199-0051
Cox-2Rabbit anti-Human, Mouse, Rat, Polyclonal, Rockland™
Manufacturer: Rockland Immunochemicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-0051-Each-of-1 | In Stock | ₹ 45,937.16 |
50-199-0051 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,937.16
GST (18%): ₹ 8,268.689
Total Price: ₹ 54,205.849
Antigen
Cox-2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTGS2
Gene Alias
Coii; Cox2; Cox-2; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; Cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; Mtco2; mt-Co2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; Prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration
55 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
P00406, P35354, P35355, Q05769
Gene Symbols
COX2, PTGS2
Immunogen
This whole rabbit serum was prepared by repeated immunizations with a fusion protein corresponding to the carboxy-terminus of human Cox-2.
Regulatory Status
RUO
Gene ID (Entrez)
19225, 26198, 29527, 5743
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antiserum is directed against human Cox-2
- Two different isoforms of the enzyme are known, Cox-1 and Cox-2
- A BLAST analysis was used to suggest cross-reactivity with Cox-2 in human, mouse and rat based on a homology with the immunizing sequence and should not cross react with Cox-1
- Reactivity against homologues from other sources is not known
- Reactivity of this antibody with Cox-2 from other species is unknown
- COX2 converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis, including production of inflammatory prostaglandins
- The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2)
- It is constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and is up-regulated under pathological conditions, such as in cancer and inflammation (in contrast to the iso-enzyme PTGS1, which is expressed ubiquitously)
- Up-regulation of COX2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis
- In cancer cells, COX2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis
- COX2 is naturally inhibited by calcitriol (the active form of Vitamin D)
- Glucocorticoids chronically trans-repress PTGS2 gene activity in vivo in part by interfering with transcription initiation and elongation
- COX2 is a target of NSAID such as aspirin, which can reduce pain and swelling from inflammation driven by COX2.
Compare Similar Items
Show Difference
Antigen: Cox-2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTGS2
Gene Alias: Coii; Cox2; Cox-2; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; Cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; Mtco2; mt-Co2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; Prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 55 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P00406, P35354, P35355, Q05769
Gene Symbols: COX2, PTGS2
Immunogen: This whole rabbit serum was prepared by repeated immunizations with a fusion protein corresponding to the carboxy-terminus of human Cox-2.
Regulatory Status: RUO
Gene ID (Entrez): 19225, 26198, 29527, 5743
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Cox-2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTGS2
Gene Alias:
Coii; Cox2; Cox-2; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; Cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; Mtco2; mt-Co2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; Prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
55 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P00406, P35354, P35355, Q05769
Gene Symbols:
COX2, PTGS2
Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a fusion protein corresponding to the carboxy-terminus of human Cox-2.
Regulatory Status:
RUO
Gene ID (Entrez):
19225, 26198, 29527, 5743
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: DRIP130
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MED23
Gene Alias: 130 kDa transcriptional co-activator; 130kDa; 133 kDa transcriptional co-activator; 3000002A17Rik; Activator-recruited cofactor 130 kDa component; ARC130; Cofactor required for Sp1 transcriptional activation subunit 3; cofactor required for Sp1 transcriptional activation, subunit 3 (130kD); CRSP complex subunit 3; CRSP130; CRSP133; CRSP3; DRIP130; ESTM7; hSur-2; Kiaa1216; MED23; Mediator complex subunit 23; mediator complex subunit MED23 variant MED23_i6; mediator complex subunit MED23 variant MED23_i7; Mediator of RNA polymerase II transcription subunit 23; mKIAA1216; MRT18; mSur-2; Protein sur-2 homolog; SUR2; SUR-2; Transcriptional coactivator CRSP130; vitamin D3 receptor interacting protein; Vitamin D3 receptor-interacting protein complex 130 kDa component; X83317
Host Species: Rabbit
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Applications: ELISA, Immunoprecipitation, Western Blot
Concentration: 85 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2
Gene Accession No.: Q80YQ2, Q9ULK4
Gene Symbols: MED23
Immunogen: This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to mouse DRIP-130 residues 897-916 (based on human DRIP-130 residue numbering) crosslinked to KLH.
Regulatory Status: RUO
Gene ID (Entrez): 70208, 9439
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Antigen:
DRIP130
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MED23
Gene Alias:
130 kDa transcriptional co-activator; 130kDa; 133 kDa transcriptional co-activator; 3000002A17Rik; Activator-recruited cofactor 130 kDa component; ARC130; Cofactor required for Sp1 transcriptional activation subunit 3; cofactor required for Sp1 transcriptional activation, subunit 3 (130kD); CRSP complex subunit 3; CRSP130; CRSP133; CRSP3; DRIP130; ESTM7; hSur-2; Kiaa1216; MED23; Mediator complex subunit 23; mediator complex subunit MED23 variant MED23_i6; mediator complex subunit MED23 variant MED23_i7; Mediator of RNA polymerase II transcription subunit 23; mKIAA1216; MRT18; mSur-2; Protein sur-2 homolog; SUR2; SUR-2; Transcriptional coactivator CRSP130; vitamin D3 receptor interacting protein; Vitamin D3 receptor-interacting protein complex 130 kDa component; X83317
Host Species:
Rabbit
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Applications:
ELISA, Immunoprecipitation, Western Blot
Concentration:
85 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2
Gene Accession No.:
Q80YQ2, Q9ULK4
Gene Symbols:
MED23
Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to mouse DRIP-130 residues 897-916 (based on human DRIP-130 residue numbering) crosslinked to KLH.
Regulatory Status:
RUO
Gene ID (Entrez):
70208, 9439
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Antigen: Cecropin B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Gene Alias: __
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Insect
Product Type: Antibody
Applications: ELISA, Immunoprecipitation, Western Blot
Concentration: 0.33 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 50% glycerol and 0.01% sodium azide; pH 7.2
Gene Accession No.: __
Gene Symbols: __
Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic full-length cecropin B corresponding to a modified sequence from that which is found in silkworm: KWKVFKKIEK VGRNIRNGIV KAGPAIAVL GEAKAL.
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Cecropin B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
__
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Insect
Product Type:
Antibody
Applications:
ELISA, Immunoprecipitation, Western Blot
Concentration:
0.33 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 50% glycerol and 0.01% sodium azide; pH 7.2
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic full-length cecropin B corresponding to a modified sequence from that which is found in silkworm: KWKVFKKIEK VGRNIRNGIV KAGPAIAVL GEAKAL.
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Smac/Diablo
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DIABLO
Gene Alias: 0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); Diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; Direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; SMAC; Smac protein; SMAC3
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Applications: ELISA, Immunoprecipitation, Western Blot
Concentration: 85 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q9NR28
Gene Symbols: DIABLO
Immunogen: This whole rabbit serum was prepared by repeated immunizations with recombinant His6-tagged human Smac/DIABLO protein (amino acids 56-239).
Regulatory Status: RUO
Gene ID (Entrez): 56616
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Smac/Diablo
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DIABLO
Gene Alias:
0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); Diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; Direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; SMAC; Smac protein; SMAC3
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Applications:
ELISA, Immunoprecipitation, Western Blot
Concentration:
85 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q9NR28
Gene Symbols:
DIABLO
Immunogen:
This whole rabbit serum was prepared by repeated immunizations with recombinant His6-tagged human Smac/DIABLO protein (amino acids 56-239).
Regulatory Status:
RUO
Gene ID (Entrez):
56616
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid